Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24938498 | 0.92 | PPID (0.50) | HTTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL18686234 | 0.89 | SYK (0.52) | HTTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL10081124 | 0.88 | LMNA (0.63) | HTTLMNASMN1; SMN2TPSAB1TPSD1 | |
| SCHEMBL18668821 | 0.88 | CYP1A2 (0.49) | HTTLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL15561412 | 0.87 | HTT (0.51) | HTTLMNASMN1; SMN2TPSAB1TPSD1 | |
| SCHEMBL23567825 | 0.86 | L3MBTL1 (0.58) | HTTLMNASMN1; SMN2TPSAB1TPSD1 | |
| SCHEMBL15561306 | 0.86 | HTT (0.50) | HTTLMNASMN1; SMN2TPSAB1TPSD1 | |
| SCHEMBL15561324 | 0.86 | HTT (0.50) | HTTLMNASMN1; SMN2TPSAB1TPSD1 | |
| SCHEMBL15561395 | 0.86 | HTT (0.50) | HTTLMNASMN1; SMN2TPSAB1TPSD1 | |
| SCHEMBL15561357 | 0.86 | HTT (0.50) | HTTLMNASMN1; SMN2TPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127461-A1 | METHODS OF SYNTHESIZING 4-VALYLOXYBUTYRIC ACID | XW LABORATORIES LIMITED (CN) | 2021-06-24 | — | — | WO | disclosed |