SCHEMBL2356905

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2358182	0.89	S1PR1 (0.48)	S1PR1S1PR3NPC1RAB9AMAPK1
	SCHEMBL2358449	0.85	ALDH1A1 (0.52)	S1PR1S1PR3NPC1RAB9AKMT2A
	SCHEMBL2359620	0.84	CPT1A (0.40)	S1PR1S1PR3NPC1RAB9AMAPK1
	SCHEMBL2358285	0.84	CYP2D6 (0.42)	S1PR1S1PR3NPC1RAB9AMAPK1
	SCHEMBL2308995	0.84	S1PR1 (0.47)	S1PR1S1PR3KMT2AMAPTTP53
	SCHEMBL2359006	0.83	ALDH1A1 (0.54)	S1PR1NPC1RAB9AMAPK1KMT2A
	SCHEMBL2357085	0.83	S1PR1 (0.53)	S1PR1S1PR3NPC1RAB9AKMT2A
	SCHEMBL2359413	0.83	SMN1; SMN2 (0.56)	NPC1RAB9AMAPK1KMT2ATSHR
	SCHEMBL2359431	0.82	S1PR1 (0.43)	S1PR1S1PR3NPC1RAB9AKMT2A
	SCHEMBL2312221	0.82	CASP3 (0.40)	S1PR1KMT2AMAPTL3MBTL1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.