Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23570044 | 0.84 | KDM4E (0.45) | MAPTKDM4EMAOBADORA2ALMNA | |
| SCHEMBL23569883 | 0.76 | KMT2A (0.44) | MAPTKDM4ERAB9AKMT2APKM | |
| SCHEMBL19808952 | 0.69 | TDP1 (0.59) | EGLN1POLBL3MBTL1MAPTKDM4E | |
| SCHEMBL20154228 | 0.68 | MAPT (0.57) | L3MBTL1MAPTKDM4EMAOBADORA2A | |
| SCHEMBL1551668 | 0.68 | PKM (0.69) | EGLN1POLBL3MBTL1KDM4ETSHR | |
| SCHEMBL28566933 | 0.68 | POLB (0.65) | EGLN1POLBL3MBTL1MAPTKDM4E | |
| SCHEMBL28041139 | 0.68 | POLB (0.57) | EGLN1POLBL3MBTL1MAPTKDM4E | |
| SCHEMBL2835796 | 0.68 | POLB (0.57) | EGLN1POLBL3MBTL1TSHRCASP3 | |
| SCHEMBL20201222 | 0.68 | POLB (0.57) | EGLN1POLBL3MBTL1MAPTKDM4E | |
| SCHEMBL23996876 | 0.67 | POLB (0.56) | EGLN1POLBL3MBTL1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |