Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23570367 | 0.84 | EGLN1 (0.46) | KDM4EMAPTMAOBADORA2AKMT2A | |
| SCHEMBL6114039 | 0.78 | ELANE (0.55) | KMT2ALMNAMEN1SMN1; SMN2ELANE | |
| SCHEMBL8426872 | 0.77 | CNR1 (0.57) | KDM4EMAPTMAOBADORA2AKMT2A | |
| SCHEMBL9400073 | 0.75 | ELANE (0.52) | KDM4EMAPTKMT2AMEN1ELANE | |
| SCHEMBL20154228 | 0.71 | MAPT (0.57) | KDM4EMAPTMAOBADORA2AKMT2A | |
| SCHEMBL9980554 | 0.68 | SLC9A1 (0.45) | KMT2ALMNAMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18031563 | 0.68 | ELANE (0.49) | KMT2AMEN1ELANENPSR1F2 | |
| SCHEMBL30302187 | 0.67 | RORC (0.54) | KDM4EKMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL590143 | 0.67 | RORC (0.41) | KDM4EKMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL17598786 | 0.66 | TDP1 (0.61) | KDM4EMAPTMAOBADORA2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |