Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324524 | 0.85 | KMT2A (0.63) | KMT2AMCL1GAAPOLBTDP1 | |
| SCHEMBL26140323 | 0.78 | FASN (0.40) | KMT2ACYP3A4EPHX1MAPTHSD11B1 | |
| SCHEMBL24658372 | 0.77 | KMT2A (0.57) | KMT2AMCL1GAAPOLBTDP1 | |
| SCHEMBL24658468 | 0.76 | KMT2A (0.51) | KMT2AMCL1GAAPOLBTDP1 | |
| SCHEMBL1963069 | 0.75 | — | — | |
| SCHEMBL12424282 | 0.72 | KMT2A (0.60) | KMT2AMCL1GAAPOLBTDP1 | |
| SCHEMBL15797043 | 0.72 | KMT2A (0.70) | KMT2AMCL1GAAPOLBTDP1 | |
| SCHEMBL6322623 | 0.72 | KMT2A (0.70) | KMT2AMCL1GAAPOLBTDP1 | |
| SCHEMBL14654974 | 0.71 | KMT2A (0.69) | KMT2AMCL1GAAPOLBTDP1 | |
| SCHEMBL25018678 | 0.71 | ATM (0.50) | KMT2AALDH1A1EPHX1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220242886-A1 | CHEMICAL COMPOUNDS | CANAAN XII L.P. | 2022-08-04 | — | — | US | disclosed |
| US-20210188879-A1 | CHEMICAL COMPOUNDS | CANAAN XII L.P. | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188879-A1 | CHEMICAL COMPOUNDS | JAK2, JAK1, JAK3 | KMT2A 616/4885MCL1 156/4885GAA 1638/4885 |
| US-20220242886-A1 | CHEMICAL COMPOUNDS | JAK2, JAK1, JAK3 | KMT2A 616/4885MCL1 156/4885GAA 1638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.