Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25117764 | 0.85 | KMT2A (0.54) | KMT2AMCL1GAAPOLBTDP1 | |
| SCHEMBL24658468 | 0.81 | KMT2A (0.51) | KMT2AMCL1GAAPOLBTDP1 | |
| SCHEMBL23570845 | 0.77 | KMT2A (0.51) | KMT2AMCL1GAAPOLBTDP1 | |
| SCHEMBL24658658 | 0.77 | HPGD (0.34) | KMT2AGAAALDH1A1L3MBTL1HPGD | |
| SCHEMBL1963069 | 0.77 | — | — | |
| SCHEMBL14631213 | 0.74 | ALDH1A1 (0.33) | ALDH1A1KDM4EL3MBTL1HPGDEPHX1 | |
| SCHEMBL12424282 | 0.74 | KMT2A (0.60) | KMT2AMCL1GAAPOLBTDP1 | |
| SCHEMBL15797043 | 0.73 | KMT2A (0.70) | KMT2AMCL1GAAPOLBTDP1 | |
| SCHEMBL6322623 | 0.73 | KMT2A (0.70) | KMT2AMCL1GAAPOLBTDP1 | |
| SCHEMBL24658686 | 0.73 | MAOA (0.39) | KMT2AGAAALDH1A1HPGDEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173756-A1 | ANTIBACTERIAL COMPOUNDS | FORGE THERAPEUTICS, INC. (US) | 2022-08-18 | — | — | WO | disclosed |