SCHEMBL2357366

SCHEMBL2357366

CCO[SiH](OC(C)=O)OC(C)=O

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.43
LMNA P02545 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 1/20 0.32
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2948698 0.95 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10TSHRTDP1
Methane SCHEMBL29183964 0.92 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TSHRTDP1
Ethylene SCHEMBL27137436 0.90 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL28880795 0.83 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10
Acetone SCHEMBL28132690 0.80 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10TSHRTDP1
SCHEMBL5702348 0.80 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL28195911 0.79 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10TSHRTDP1
Acetic Acid SCHEMBL2248274 0.78 FFAR3 (0.41) ALDH1A1LMNAHSD17B10TSHRTDP1
SCHEMBL7054491 0.77
SCHEMBL203518 0.76 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP disclosed
EP-3074450-B1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MAT INC (US) 2020-11-11 EP disclosed
CN-105793326-B Moisture-curable compositions with metal-arene complexes 莫门蒂夫性能材料股份有限公司 2020-07-21 CN disclosed
US-10174169-B2 Moisture curable compound with metal-arene complexes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-01-08 US disclosed
EP-3262128-B1 CURABLE SILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MAT INC (US) 2018-11-21 EP disclosed
US-10023699-B2 Curable siloxane compositions MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2018-07-17 US disclosed
US-9944770-B2 Moisture curable compound with thiourea MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-04-17 US disclosed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US disclosed
US-20180002492-A1 CURABLE SILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. 2018-01-04 US disclosed
EP-3262128-A1 CURABLE SILOXANE COMPOSITIONS Momentive Performance Materials Inc. (US) 2018-01-03 EP disclosed
WO-2015003045-A1 MOISTURE CURABLE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC (US) 2015-01-08 WO disclosed
US-20150005443-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2015-01-01 US disclosed
WO-2014210492-A1 MOISTURE CURABLE COMPOSITION WITH STRONTIUM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-12-31 WO disclosed
WO-2014205251-A2 MOISTURE CURABLE COMPOUND WITH THIOUREA MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-12-24 WO disclosed
EP-2797692-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION Momentive Performance Materials Inc. (US) 2014-11-05 EP disclosed
WO-2013165552-A2 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC (US) 2013-11-07 WO disclosed
WO-2013158236-A2 MOSITURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-10-24 WO disclosed
WO-2013101755-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-07-04 WO disclosed
EP-1448714-B1 SYNTHESIS AND USE ALKYLALKOXYACYLOXYSILANES AND BLENDS THEREOF FOR USE AS A CROSSLINKING AGENT IN MOISTURE CURING RTV'S MOMENTIVE PERFORMANCE MAT INC (US) 2011-08-24 EP disclosed
US-4220748-A CONTAINING AN ACETOXY GROUP-CONTAINING SILANE COMPOUND TOSHIBA SILICONE CO., LTD. (JP) 1980-09-02 US disclosed