Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL28132690 | 0.91 | ALDH1A1 (0.43) | FFAR3ALDH1A1LMNAHSD17B10TDP1 | |
| Carbamic Acid SCHEMBL20814677 | 0.86 | ALOX15 (0.43) | FFAR3ALDH1A1LMNAHSD17B10ALOX15 | |
| Methacrylic Acid SCHEMBL1419612 | 0.85 | THRB (0.38) | ALDH1A1LMNAHSD17B10TDP1MGAM | |
| SCHEMBL22491271 | 0.83 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10HCAR2GLO1 | |
| Urea SCHEMBL9068018 | 0.82 | ALOX15 (0.46) | ALDH1A1LMNAHSD17B10TDP1ALOX15 | |
| Methyl Alcohol SCHEMBL27815477 | 0.81 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL35885 | 0.80 | — | — | |
| SCHEMBL28028831 | 0.80 | — | — | |
| Acrylic Acid SCHEMBL31139542 | 0.79 | LMNA (0.48) | ALDH1A1LMNAHSD17B10ALOX15TSHR | |
| SCHEMBL27995375 | 0.79 | ALDH1A1 (0.30) | ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946068-B2 | Patterned doping of semiconductor substrates using photosensitive monolayers | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-02-03 | — | — | US | disclosed |
| US-20130330918-A1 | PATTERNED DOPING OF SEMICONDUCTOR SUBSTRATES USING PHOTOSENSITIVE MONOLAYERS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-12-12 | — | — | US | disclosed |
| US-8513642-B2 | Patterned doping of semiconductor substrates using photosensitive monolayers | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-08-20 | — | — | US | disclosed |
| US-8354333-B2 | Patterned doping of semiconductor substrates using photosensitive monolayers | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-01-15 | — | — | US | disclosed |
| US-20120273925-A1 | PATTERNED DOPING OF SEMICONDUCTOR SUBSTRATES USING PHOTOSENSITIVE MONOLAYERS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-11-01 | — | — | US | disclosed |
| US-20110186969-A1 | PATTERNED DOPING OF SEMICONDUCTOR SUBSTRATES USING PHOTOSENSITIVE MONOLAYERS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-08-04 | — | — | US | disclosed |
| US-4152286-A | USES TWO SOLVENTS WITH DIFFERENT BOILING POINTS | TEXAS INSTRUMENTS INCORPORATED (US) | 1979-05-01 | — | — | US | disclosed |