Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 15/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.57 |
| ▸ | SELL | P14151 | 1/20 | 0.49 |
| ▸ | SELP | P16109 | 1/20 | 0.49 |
| ▸ | SELE | P16581 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19710224 | 1.00 | SMYD3 (0.61) | SMYD3SIGMAR1SELLSELPSELE | |
| SCHEMBL19710155 | 0.85 | SMYD3 (0.61) | SMYD3SIGMAR1 | |
| SCHEMBL21490175 | 0.85 | SMYD3 (0.61) | SMYD3SIGMAR1 | |
| SCHEMBL21490141 | 0.85 | SIGMAR1 (0.56) | SMYD3SIGMAR1SELLSELPSELE | |
| SCHEMBL19701362 | 0.85 | SIGMAR1 (0.56) | SMYD3SIGMAR1SELLSELPSELE | |
| SCHEMBL6874316 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL5114877 | 0.77 | SMYD3 (0.57) | SMYD3 | |
| SCHEMBL21489852 | 0.77 | SMYD3 (0.56) | SMYD3 | |
| SCHEMBL19710379 | 0.77 | SMYD3 (0.56) | SMYD3 | |
| SCHEMBL30590284 | 0.76 | LMNA (0.52) | SMYD3SIGMAR1SELLSELPSELE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198252-A1 | SMYD INHIBITORS | EPIZYME INC (US) | 2021-07-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198252-A1 | SMYD INHIBITORS | SMYD3, SMYD2, SMURF2 | SMYD3 1/4885SIGMAR1 1193/4885SELL 4438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.