Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.71 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.71 |
| ▸ | KDR | P35968 | 2/20 | 0.71 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP14 | P31944 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | CASP4 | P49662 | 1/20 | 0.49 |
| ▸ | CASP5 | P51878 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CASP9 | P55211 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.49 |
| ▸ | CASP12 | Q6UXS9 | 1/20 | 0.49 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 3/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909686 | 0.90 | EGFR (0.52) | EGFRPDGFRBKDRCASP1CASP14 | |
| SCHEMBL23577069 | 0.90 | EGFR (0.52) | EGFRPDGFRBKDRCASP1CASP14 | |
| SCHEMBL2257339 | 0.84 | EGFR (1.00) | EGFRPDGFRBKDRCASP1CASP14 | |
| Hydrochloric Acid SCHEMBL1685084 | 0.83 | EGFR (0.97) | EGFRPDGFRBKDRCASP1CASP14 | |
| SCHEMBL23576745 | 0.81 | MAPT (0.41) | EGFRPDGFRBKDRMAPTSMN1; SMN2 | |
| SCHEMBL23577222 | 0.81 | PDE5A (0.44) | EGFRPDGFRBKDRSMN1; SMN2 | |
| SCHEMBL30961004 | 0.81 | PDE5A (0.44) | EGFRPDGFRBKDRSMN1; SMN2 | |
| SCHEMBL29909588 | 0.79 | ALDH1A1 (0.48) | EGFRPDGFRBKDRCASP1CASP14 | |
| SCHEMBL23578005 | 0.79 | ALDH1A1 (0.48) | EGFRPDGFRBKDRCASP1CASP14 | |
| SCHEMBL23577048 | 0.79 | CSF1R (0.49) | EGFRPDGFRBKDRCASP1CASP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |