Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.52 |
| ▸ | KDR | P35968 | 4/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP14 | P31944 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | CASP4 | P49662 | 1/20 | 0.50 |
| ▸ | CASP5 | P51878 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CASP9 | P55211 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.50 |
| ▸ | CASP12 | Q6UXS9 | 1/20 | 0.50 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577069 | 1.00 | EGFR (0.52) | EGFRPDGFRBKDRCASP1CASP14 | |
| SCHEMBL23577413 | 0.90 | EGFR (0.71) | EGFRPDGFRBKDRCASP1CASP14 | |
| SCHEMBL30961004 | 0.87 | PDE5A (0.44) | EGFRPDGFRBKDRSMN1; SMN2 | |
| SCHEMBL23577222 | 0.87 | PDE5A (0.44) | EGFRPDGFRBKDRSMN1; SMN2 | |
| SCHEMBL29909776 | 0.87 | DYRK1A (0.44) | EGFRPDGFRBKDRSMN1; SMN2 | |
| SCHEMBL23601282 | 0.87 | DYRK1A (0.44) | EGFRPDGFRBKDRSMN1; SMN2 | |
| SCHEMBL29909632 | 0.87 | EGFR (0.40) | EGFRPDGFRBKDRCASP1CASP14 | |
| SCHEMBL23577808 | 0.87 | EGFR (0.40) | EGFRPDGFRBKDRCASP1CASP14 | |
| SCHEMBL23577877 | 0.86 | SMN1; SMN2 (0.43) | EGFRPDGFRBKDRKDM4ESMN1; SMN2 | |
| SCHEMBL23578005 | 0.86 | ALDH1A1 (0.48) | EGFRPDGFRBKDRCASP1CASP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |