Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 6/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 12/20 | 0.46 |
| ▸ | CDK1 | P06493 | 12/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 12/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 12/20 | 0.46 |
| ▸ | CDK2 | P24941 | 12/20 | 0.46 |
| ▸ | CDK9 | P50750 | 12/20 | 0.46 |
| ▸ | CDK4 | P11802 | 10/20 | 0.46 |
| ▸ | CCND1 | P24385 | 10/20 | 0.46 |
| ▸ | CDK7 | P50613 | 11/20 | 0.45 |
| ▸ | CCNH | P51946 | 11/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356680 | 0.89 | KCNH3 (0.54) | TNK2CCNT1CDK1CCNB1CCNE1 | |
| SCHEMBL2357973 | 0.86 | CCNT1 (0.47) | TNK2CCNT1CDK1CCNB1CCNE1 | |
| SCHEMBL2281856 | 0.86 | CCNT1 (0.58) | TNK2CCNT1CDK1CCNB1CCNE1 | |
| SCHEMBL2356729 | 0.86 | CDK2 (0.56) | TNK2CCNT1CDK1CCNB1CCNE1 | |
| SCHEMBL2289888 | 0.85 | CCNT1 (0.60) | TNK2CCNT1CDK1CCNB1CCNE1 | |
| SCHEMBL2354958 | 0.84 | PAK4 (0.53) | CCNT1CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL2353643 | 0.84 | CCNT1 (0.62) | TNK2CCNT1CDK1CCNB1CCNE1 | |
| SCHEMBL2278859 | 0.84 | CDK2 (0.47) | TNK2CCNT1CDK1CCNB1CCNE1 | |
| SCHEMBL2286461 | 0.84 | CCNT1 (0.45) | TNK2CCNT1CDK1CCNB1CCNE1 | |
| SCHEMBL2281532 | 0.83 | CDK2 (0.51) | TNK2CCNT1CDK1CCNB1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | TNK2 2063/4885CCNT1 513/4885CDK1 793/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | TNK2 2134/4885CCNT1 528/4885CDK1 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.