Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20772175 | 0.87 | TP53 (0.77) | TP53MEN1KMT2ALMNAHTT | |
| SCHEMBL30044815 | 0.86 | TP53 (0.57) | USP5TP53MEN1KMT2ALMNA | |
| SCHEMBL20772311 | 0.85 | TP53 (0.79) | USP5TP53MEN1KMT2ALMNA | |
| SCHEMBL20772177 | 0.82 | TP53 (0.75) | USP5TP53MEN1KMT2ALMNA | |
| SCHEMBL29716504 | 0.81 | SMN1; SMN2 (0.61) | TP53MEN1KMT2ALMNAHTT | |
| SCHEMBL29264663 | 0.81 | GAA (0.58) | MEN1KMT2ALMNAGAAALDH1A1 | |
| SCHEMBL23577489 | 0.79 | TP53 (0.50) | USP5TP53MEN1KMT2ALMNA | |
| SCHEMBL4161092 | 0.79 | HTR2C (0.51) | TP53MEN1KMT2ALMNAHTT | |
| SCHEMBL28818511 | 0.78 | HSD11B1 (0.60) | MEN1KMT2ALMNAHTTGAA | |
| SCHEMBL22688634 | 0.77 | HTR2C (0.50) | TP53MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081509-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | Zydus Lifesciences Limited (IN) | 2022-11-02 | — | — | EP | disclosed |
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2021130723-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | CADILA HEALTHCARE LIMITED (IN) | 2021-07-01 | — | — | WO | disclosed |