Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 11/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29959019 | 1.00 | NR1H2 (0.43) | NR1H2DDB1CRBNRORCKDM4E | |
| SCHEMBL15740984 | 1.00 | NR1H2 (0.43) | NR1H2DDB1CRBNRORCKDM4E | |
| SCHEMBL23579468 | 0.87 | DDB1 (0.43) | NR1H2DDB1CRBNRORCKDM4E | |
| SCHEMBL12488892 | 0.82 | RORC (0.44) | NR1H2DDB1CRBNRORCKDM4E | |
| SCHEMBL19555254 | 0.82 | RORC (0.44) | NR1H2DDB1CRBNRORCKDM4E | |
| SCHEMBL15742012 | 0.82 | DDB1 (0.39) | NR1H2DDB1CRBNRORCKDM4E | |
| SCHEMBL5133428 | 0.81 | RORC (0.43) | NR1H2DDB1CRBNRORCUSP2 | |
| SCHEMBL12364068 | 0.81 | NR1H2 (0.40) | NR1H2DDB1CRBNRORCUSP2 | |
| SCHEMBL26007583 | 0.80 | DDB1 (0.38) | NR1H2DDB1CRBNRORCKDM4E | |
| SCHEMBL15743105 | 0.80 | DDB1 (0.38) | NR1H2DDB1CRBNRORCKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081515-A1 | INHIBITORS OF MUTANT FORMS OF EGFR | Blueprint Medicines Corporation (US) | 2022-11-02 | — | — | EP | disclosed |
| WO-2021133809-A1 | INHIBITORS OF MUTANT FORMS OF EGFR | BLUEPRINT MEDICINES CORPORATION (US) | 2021-07-01 | — | — | WO | disclosed |