Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3869335 | 0.84 | LMNA (0.51) | LMNARNPEPGAAALDH1A1L3MBTL1 | |
| SCHEMBL14404929 | 0.84 | LMNA (0.51) | LMNARNPEPGAAALDH1A1L3MBTL1 | |
| SCHEMBL3869337 | 0.84 | LMNA (0.51) | LMNARNPEPGAAALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11125960 | 0.82 | LMNA (0.50) | LMNARNPEPGAAALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28941784 | 0.82 | LMNA (0.50) | LMNARNPEPGAAALDH1A1L3MBTL1 | |
| SCHEMBL14374795 | 0.82 | LMNA (0.40) | LMNARNPEPGAAALDH1A1L3MBTL1 | |
| SCHEMBL19487362 | 0.81 | LMNA (0.39) | LMNARNPEPGAAALDH1A1L3MBTL1 | |
| SCHEMBL10296095 | 0.81 | L3MBTL1 (0.51) | GAAALDH1A1L3MBTL1USP2 | |
| SCHEMBL19277382 | 0.81 | — | — | |
| SCHEMBL10296118 | 0.81 | LMNA (0.42) | LMNARNPEPGAAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842459-A1 | ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF | ImmunoGen, Inc. (US) | 2021-06-30 | — | — | EP | disclosed |