Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 1/20 | 0.47 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.47 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.47 |
| ▸ | DUOX2 | Q9NRD8 | 1/20 | 0.47 |
| ▸ | DUOX1 | Q9NRD9 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | TLR5 | O60602 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16560732 | 0.86 | CYBB (0.63) | CYBBNOX5NOX4DUOX2DUOX1 | |
| SCHEMBL9476085 | 0.70 | ALDH1A1 (0.56) | MAPTALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL9476934 | 0.70 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL15313075 | 0.66 | CYBB (0.69) | CYBBNOX5NOX4DUOX2DUOX1 | |
| SCHEMBL15748203 | 0.65 | TLR5 (0.48) | TLR5SMN1; SMN2GSK3BCYP1A2CYP2C19 | |
| SCHEMBL9476371 | 0.62 | LMNA (0.53) | ALDH1A1LMNAHPGDNPSR1TP53 | |
| SCHEMBL16157059 | 0.61 | SMN1; SMN2 (0.84) | SMN1; SMN2TDP1GSK3BCYP1A2CYP2C19 | |
| SCHEMBL7697588 | 0.60 | GSK3B (0.51) | TLR5SMN1; SMN2GSK3BCYP1A2CYP2C19 | |
| SCHEMBL4930461 | 0.60 | CYBB (0.57) | CYBBNOX5NOX4DUOX2DUOX1 | |
| SCHEMBL12897993 | 0.59 | HPGD (0.70) | SMN1; SMN2GSK3BCYP1A2CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041469-B1 | TREATMENT AND OR PREVENTION OF METASTATIC PROSTATE CANCER | UNIV ARIZONA (US) | 2021-06-30 | — | — | EP | disclosed |