Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21760563 | 0.85 | KDM1A (0.43) | KDM1ACYP11B1CYP11B2NT5E | |
| SCHEMBL30978728 | 0.71 | KDM1A (0.47) | KDM1ACYP11B1CYP11B2NT5E | |
| SCHEMBL695877 | 0.71 | KDM1A (0.47) | KDM1ACYP11B1CYP11B2NT5E | |
| SCHEMBL30978721 | 0.71 | KDM1A (0.47) | KDM1ACYP11B1CYP11B2NT5E | |
| SCHEMBL30864218 | 0.70 | KDM1A (0.50) | KDM1ACYP11B1CYP11B2NT5E | |
| SCHEMBL6267032 | 0.70 | KDM1A (0.50) | KDM1ACYP11B1CYP11B2NT5E | |
| SCHEMBL672252 | 0.69 | NOTUM (0.47) | KDM1ACYP11B1CYP11B2NT5E | |
| SCHEMBL8883394 | 0.69 | KDM1A (0.44) | KDM1ACYP11B1CYP11B2NT5E | |
| SCHEMBL29514712 | 0.67 | CYP11B2 (0.53) | KDM1ACYP11B1CYP11B2 | |
| SCHEMBL56867 | 0.67 | CYP11B2 (0.53) | KDM1ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842439-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-06-30 | — | — | EP | disclosed |