SCHEMBL29514712

SCHEMBL29514712

Fc1cc(Br)ccc1C(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 4/20 0.53
CYP11B1 P15538 2/20 0.53
KIF11 P52732 12/20 0.48
KDM1A O60341 3/20 0.44
DGAT1 O75907 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56867 1.00 CYP11B2 (0.53) CYP11B2CYP11B1KIF11KDM1ADGAT1
SCHEMBL15744302 0.86 DGAT1 (0.41) CYP11B2CYP11B1KIF11KDM1ADGAT1
SCHEMBL18285726 0.82 CYP11B1 (0.39) CYP11B2CYP11B1KIF11KDM1ADGAT1
SCHEMBL5361521 0.82 CYP11B1 (0.39) CYP11B2CYP11B1KIF11KDM1ADGAT1
SCHEMBL29988758 0.82 CYP11B1 (0.39) CYP11B2CYP11B1KIF11KDM1ADGAT1
SCHEMBL415598 0.82 CYP11B1 (0.39) CYP11B2CYP11B1KIF11KDM1ADGAT1
SCHEMBL690073 0.81 PTPN7 (0.47) CYP11B2CYP11B1KDM1ADGAT1
SCHEMBL29890371 0.81 PTPN7 (0.47) CYP11B2CYP11B1KDM1ADGAT1
SCHEMBL6267032 0.80 KDM1A (0.50) CYP11B2CYP11B1KDM1A
SCHEMBL30864218 0.80 KDM1A (0.50) CYP11B2CYP11B1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743085-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Tenvie Therapeutics, Inc. (US) 2026-05-20 EP disclosed
EP-4713327-A1 SPIRO DERIVATIVES AS WRN INHIBITORS Insilico Medicine IP Limited (HK) 2026-03-25 EP disclosed
EP-4695241-A1 THIADIAZOLONE DERIVATIVES, COMPOSITIONS AND USES THEREOF Danatlas Pharmaceuticals Co., Ltd. (CN) 2026-02-18 EP disclosed
EP-4634161-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Tenvie Therapeutics Inc. (US) 2025-10-22 EP disclosed
EP-4592308-A1 CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-30 EP disclosed
CN-120202211-A Cyclic compounds having selective KRAS inhibition over HRAS and NRAS 中外制药株式会社 2025-06-24 CN disclosed
CN-120152972-A Thiadiazole derivative, composition and application thereof 北京丹擎医药科技有限公司 2025-06-13 CN disclosed
WO-2025119195-A1 COMBINATION OF POLQ INHIBITOR AND ANTI-CANCER THERAPEUTIC AGENT DANATLAS PHARMACEUTICALS CO., LTD. (CN) 2025-06-12 WO disclosed
CN-120077028-A Thiadiazole derivative, composition and application thereof 北京丹擎医药科技有限公司 2025-05-30 CN disclosed
EP-4532496-A1 NOVEL PAR-2 INHIBITORS Domain Therapeutics (FR) 2025-04-09 EP disclosed
CN-111936503-B Oxazine monoacylglycerol lipase (MAGL) inhibitors 豪夫迈·罗氏有限公司 2023-09-12 CN disclosed
EP-4237404-A1 NOVEL COMPOUNDS Sitryx Therapeutics Limited (GB) 2023-09-06 EP disclosed
CN-111315744-B Heteroaryl tetrahydropyridine compound, preparation method, pharmaceutical composition and application thereof 四川科伦博泰生物医药股份有限公司 2023-07-14 CN disclosed
CN-110740991-B Novel biphenyl compound or salt thereof 大鹏药品工业株式会社 2023-07-04 CN disclosed
WO-2023063301-A1 METHOD FOR PRODUCING FLUORINATED AROMATIC COMPOUND ダイキン工業株式会社 2023-04-20 WO disclosed
WO-2022269251-A1 ACRYLAMIDE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS SITRYX THERAPEUTICS LIMITED (GB) 2022-12-29 WO disclosed
CN-114846015-A Substituted heteroaryl compounds useful as T cell activators 百时美施贵宝公司 2022-08-02 CN disclosed
CN-110857298-B Heteroaryl tetrahydropyridines, pharmaceutical compositions containing same, preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2022-05-10 CN disclosed
WO-2022090724-A1 NOVEL COMPOUNDS SITRYX THERAPEUTICS LIMITED (GB) 2022-05-05 WO disclosed
CN-114258390-A Glycolate oxidase inhibitors for disease treatment 生物马林药物股份有限公司 2022-03-29 CN disclosed