Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23585754 | 0.90 | STING1 (0.36) | RAB9ALMNAEPHX2KDM4ESMN1; SMN2 | |
| SCHEMBL21766454 | 0.90 | STING1 (0.42) | STING1 | |
| SCHEMBL21766440 | 0.79 | STING1 (0.42) | STING1 | |
| SCHEMBL21766433 | 0.79 | STING1 (0.36) | RAB9ASTING1 | |
| SCHEMBL21766438 | 0.79 | STING1 (0.42) | STING1 | |
| SCHEMBL23585793 | 0.78 | STING1 (0.43) | STING1 | |
| SCHEMBL21766224 | 0.77 | STING1 (0.39) | STING1 | |
| SCHEMBL21766533 | 0.74 | LMNA (0.32) | LMNASTING1TSHR | |
| SCHEMBL21766531 | 0.74 | STING1 (0.41) | STING1PIK3CA | |
| SCHEMBL21766140 | 0.72 | STING1 (0.58) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842437-A1 | HIGH ACTIVITY STING PROTEIN AGONIST | Adlai Nortye Biopharma Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |