Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948066 | 0.86 | SMN1; SMN2 (0.43) | RNASEH1ARALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL15662204 | 0.84 | RNASEH1 (0.40) | RNASEH1ARALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL20477326 | 0.83 | RNASEH1 (0.53) | RNASEH1ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL16669003 | 0.80 | MEN1 (0.43) | RNASEH1ARSMN1; SMN2KMT2AHTT | |
| SCHEMBL19780485 | 0.74 | MAPK1 (0.40) | ALDH1A1NPSR1KMT2AHTTKDM4E | |
| SCHEMBL7425208 | 0.74 | MAPK1 (0.40) | ALDH1A1NPSR1KMT2AKDM4EMAPT | |
| SCHEMBL1966536 | 0.72 | PDE3B (0.48) | ALDH1A1SMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL30392579 | 0.71 | NPSR1 (0.47) | ALDH1A1NPSR1PARP1GAA | |
| SCHEMBL949159 | 0.71 | MMP2 (0.56) | RNASEH1ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL27884838 | 0.71 | NPSR1 (0.44) | ALDH1A1HPGDSMN1; SMN2NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842420-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners LLC (US) | 2021-06-30 | — | — | EP | disclosed |