Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.49 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22604445 | 1.00 | PDE2A (0.49) | PDE2ATRPV3NOS3NOS1NOS2 | |
| SCHEMBL19153177 | 0.80 | TACR1 (0.40) | PDE2AALDH1A1DPP7 | |
| SCHEMBL435755 | 0.79 | PDE2A (0.52) | PDE2AALDH1A1CES2CES1MC4R | |
| SCHEMBL13622230 | 0.79 | PDE2A (0.52) | PDE2AALDH1A1CES2CES1MC4R | |
| SCHEMBL28347282 | 0.79 | PDE2A (0.52) | PDE2AALDH1A1CES2CES1MC4R | |
| SCHEMBL13328621 | 0.79 | PDE2A (0.50) | PDE2AALDH1A1CES2CES1 | |
| SCHEMBL12086293 | 0.79 | PDE2A (0.50) | PDE2AALDH1A1CES2CES1 | |
| SCHEMBL18896394 | 0.78 | PNMT (0.50) | ALDH1A1CES2MC4RCYP3A4 | |
| SCHEMBL13126259 | 0.77 | PDE2A (0.48) | PDE2AALDH1A1CES2CES1MC4R | |
| SCHEMBL12738658 | 0.77 | TRPA1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3679085-B1 | MODIFIED POLYARYL ETHER KETONES | SOLVAY SPECIALTY POLYMERS IT (IT) | 2021-06-30 | — | — | EP | disclosed |