Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22872467 | 0.78 | HRH1 (0.50) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| SCHEMBL21872596 | 0.73 | HRH1 (0.52) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| SCHEMBL2722250 | 0.73 | ALDH1A1 (0.57) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| SCHEMBL1760708 | 0.69 | HRH1 (0.52) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| SCHEMBL1760709 | 0.69 | HRH1 (0.52) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| Lithium Ion SCHEMBL28463950 | 0.69 | CYP1A2 (0.56) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| SCHEMBL18901920 | 0.69 | HRH3 (0.47) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| SCHEMBL29485678 | 0.69 | HRH1 (0.73) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| SCHEMBL230753 | 0.69 | HRH1 (0.73) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| SCHEMBL27877150 | 0.69 | HRH3 (0.50) | HRH3HRH1ALDH1A1LMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842436-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING IMIDAZOPYRIMIDINE OR IMIDAZOTRIAZINE DERIVATIVES FOR USE IN THE TREATMENT OF SCHIZOPHRENIA | SK Biopharmaceuticals Co., Ltd. (KR) | 2021-06-30 | — | — | EP | disclosed |