Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16092088 | 0.82 | CDC25B (0.43) | CDC25BCNR2CNR1MEN1KMT2A | |
| SCHEMBL16061985 | 0.74 | CYP1A2 (0.42) | CNR2CNR1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2475368 | 0.68 | GAA (0.35) | ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL16092097 | 0.66 | CDC25B (0.48) | CDC25BCNR2CNR1MEN1KMT2A | |
| SCHEMBL16092091 | 0.66 | PTPN1 (0.48) | CNR2CNR1MEN1KMT2AALDH1A1 | |
| SCHEMBL16061977 | 0.65 | CCNC (0.40) | CNR2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL27738535 | 0.63 | LOXL2 (0.37) | THRBPOLB | |
| SCHEMBL29702036 | 0.61 | CDC25B (0.57) | CDC25BMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL26117107 | 0.61 | CDC25B (0.57) | CDC25BMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL25310527 | 0.61 | CES2 (0.46) | KMT2AALDH1A1L3MBTL1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842424-A1 | MAP KINASE MODULATORS AND USES THEREOF IN THE TRETAMENT OF TAUOPATHIES | The Trustees of Columbia University in the City of New York (US) | 2021-06-30 | — | — | EP | disclosed |