SCHEMBL23587161

SCHEMBL23587161

CC1C=CC=C(N)C1c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.33
MAOA P21397 9/20 0.33
KDM1A O60341 7/20 0.33
CYP2C19 P33261 6/20 0.33
CYP2B6 P20813 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33
LMNA P02545 2/20 0.33
TAAR1 Q96RJ0 2/20 0.33
SLC6A3 Q01959 2/20 0.33
CYP3A4 P08684 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
CYP2A6 P11509 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
DRD3 P35462 1/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032412 0.69 NOS1 (0.38) CYP2C19CYP1A2CYP2C9LMNATAAR1
SCHEMBL24302591 0.68
SCHEMBL26544762 0.68
SCHEMBL10083387 0.68
SCHEMBL24302593 0.68
SCHEMBL27355456 0.68
SCHEMBL24786362 0.67 CASP1 (0.35) CYP3A4MEN1KMT2AKDM4E
SCHEMBL21546182 0.67 HSD17B10 (0.32) TAAR1CYP3A4HSD17B10
SCHEMBL20115119 0.66
SCHEMBL28036409 0.66 CYP2C19 (0.42) MAOBMAOAKDM1ACYP2C19CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3842444-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2021-06-30 EP disclosed