Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19127270 | 0.75 | ELANE (0.42) | HTR3A | |
| SCHEMBL30711997 | 0.75 | ELANE (0.42) | HTR3A | |
| SCHEMBL15723742 | 0.66 | GRM4 (0.43) | ESR1 | |
| SCHEMBL27702080 | 0.62 | ABL1 (0.41) | ESR1 | |
| SCHEMBL492329 | 0.61 | ALDH1A1 (0.44) | HTR3A | |
| SCHEMBL30147561 | 0.61 | CSNK2A1 (0.42) | — | |
| SCHEMBL19128146 | 0.61 | ELANE (0.42) | — | |
| SCHEMBL29301466 | 0.61 | CSNK2A1 (0.42) | — | |
| SCHEMBL31632866 | 0.60 | NOTUM (0.42) | — | |
| SCHEMBL23093693 | 0.60 | ELANE (0.49) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652168-B1 | 5-MEMBERED AND BICYCLIC HETEROCYCLIC AMIDES AS INHIBITORS OF ROCK | BRISTOL MYERS SQUIBB CO (US) | 2021-06-30 | — | — | EP | disclosed |