Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.51 |
| ▸ | WNT3A | P56704 | 3/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 3/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070398 | 1.00 | CTNNB1 (0.51) | CTNNB1WNT3ASMYD3ALDH1A1CYP1A2 | |
| SCHEMBL11434846 | 0.87 | CTNNB1 (0.54) | CTNNB1WNT3ASMYD3ADORA3ADORA2A | |
| SCHEMBL31070402 | 0.82 | HTR1B (0.52) | CTNNB1WNT3ASMYD3ADORA3ADORA2A | |
| SCHEMBL31070403 | 0.82 | HTR1B (0.52) | CTNNB1WNT3ASMYD3ADORA3ADORA2A | |
| SCHEMBL5595558 | 0.80 | CNR1 (0.54) | CTNNB1WNT3AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL31070399 | 0.80 | PGR (0.51) | CTNNB1WNT3ASMYD3ADORA3ADORA2A | |
| SCHEMBL1347343 | 0.78 | CTNNB1 (0.58) | CTNNB1WNT3ASMYD3TAS2R8GPR183 | |
| SCHEMBL10407674 | 0.78 | CTNNB1 (0.61) | CTNNB1WNT3ASMYD3GPR183MRGPRX4 | |
| SCHEMBL758294 | 0.78 | KDM4E (0.47) | CTNNB1WNT3ASMYD3ALDH1A1 | |
| SCHEMBL22902082 | 0.77 | SMYD3 (0.53) | CTNNB1WNT3ASMYD3ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349966-A1 | NEW ANALOGS OF POLYSPHORIN AND USES THEREOF FOR TREATING OR PREVENTING MALARIA | Assistance Publique - Hôpitaux de Paris (FR) | 2011-08-03 | — | — | EP | disclosed |
| EP-2177496-A1 | New analogs of polysphorin and uses thereof for treating or preventing malaria | Assistance Publique - Hopitaux de Paris (FR) | 2010-04-21 | — | — | EP | disclosed |
| EP-2177496-A1 | New analogs of polysphorin and uses thereof for treating or preventing malaria | Assistance Publique - Hopitaux de Paris (FR) | 2010-04-21 | — | — | EP | disclosed |
| WO-2010040730-A1 | NEW ANALOGS OF POLYSPHORIN AND USES THEREOF FOR TREATING OR PREVENTING MALARIA | ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS (FR) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010040730-A1 | NEW ANALOGS OF POLYSPHORIN AND USES THEREOF FOR TREATING OR PREVENTING MALARIA | ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS (FR) | 2010-04-15 | — | — | WO | disclosed |