SCHEMBL31070403

SCHEMBL31070403

CNC(C)C(=O)c1ccc2c(c1)OC(F)(F)O2

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 2/20 0.52
CTNNB1 P35222 3/20 0.49
WNT3A P56704 3/20 0.49
SMYD3 Q9H7B4 3/20 0.46
PDE2A O00408 3/20 0.39
ADORA3 P0DMS8 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA2B P29275 1/20 0.39
ADORA1 P30542 1/20 0.39
CHRNA1 P02708 1/20 0.38
CHRNG P07510 1/20 0.38
CHRNB1 P11230 1/20 0.38
CHRNB2 P17787 1/20 0.38
SLC6A2 P23975 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA4 P43681 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CHRND Q07001 1/20 0.38
HDAC4 P56524 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31070402 1.00 HTR1B (0.52) HTR1BCTNNB1WNT3ASMYD3PDE2A
SCHEMBL25665024 0.87 HTR1B (0.50) HTR1BCTNNB1WNT3ASMYD3CHRNA1
SCHEMBL25745352 0.85 HTR1B (0.49) HTR1BCTNNB1WNT3ASMYD3CHRNA1
SCHEMBL25745430 0.85 HTR1B (0.49) HTR1BCTNNB1WNT3ASMYD3CHRNA1
SCHEMBL11434846 0.84 CTNNB1 (0.54) CTNNB1WNT3ASMYD3PDE2AADORA3
SCHEMBL25745310 0.84 HTR1B (0.48) HTR1BCTNNB1WNT3ASMYD3CHRNA1
SCHEMBL2358745 0.82 CTNNB1 (0.51) CTNNB1WNT3ASMYD3PDE2AADORA3
SCHEMBL31070398 0.82 CTNNB1 (0.51) CTNNB1WNT3ASMYD3PDE2AADORA3
SCHEMBL30376331 0.78 SMYD3 (0.57) CTNNB1WNT3ASMYD3TAS2R8
SCHEMBL22902082 0.78 SMYD3 (0.53) CTNNB1WNT3ASMYD3PDE2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673127-A1 DEUTERATED AND FLUORINATED EMPATHOGENS Alexander Shulgin Research Institute, Inc. (US) 2026-01-07 EP disclosed
WO-2024182774-A1 DEUTERATED AND FLUORINATED EMPATHOGENS ALEXANDER SHULGIN RESEARCH INSTITUTE, INC. (US) 2024-09-06 WO disclosed