Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13363795 | 1.00 | GABRA1 (0.38) | GABRA1GABRB2MAPTGAARAB9A | |
| SCHEMBL10655491 | 0.81 | USP2 (0.47) | GABRA1GABRB2MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2161080 | 0.81 | USP2 (0.47) | GABRA1GABRB2MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2161081 | 0.81 | USP2 (0.47) | GABRA1GABRB2MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL21999447 | 0.79 | GAA (0.34) | MAPTGAARAB9ASMN1; SMN2TSHR | |
| SCHEMBL14987827 | 0.79 | L3MBTL1 (0.42) | MAPTGAARAB9ASMN1; SMN2TSHR | |
| SCHEMBL22908188 | 0.78 | GABRA1 (0.34) | GABRA1GABRB2MAPTGAASMN1; SMN2 | |
| SCHEMBL10339443 | 0.78 | MAPT (0.38) | GABRA1GABRB2MAPTGAARAB9A | |
| SCHEMBL11406375 | 0.78 | SIRT2 (0.46) | MAPTGAARAB9ATSHRKDM4E | |
| Methylamine SCHEMBL10879151 | 0.78 | USP2 (0.45) | GABRA1GABRB2MAPTRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158463-A1 | DIAMINE-LINKED RECEPTOR-SPECIFIC CYCLIC PEPTIDES | PALATIN TECHNOLOGIES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2021158464-A1 | REVERSE AMIDE-LINKED MELANOCORTIN RECEPTOR-SPECIFIC CYCLIC PEPTIDES | PALATIN TECHNOLOGIES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
| US-20210198201-A1 | Orally Active Melanocortin Receptor-4 Compounds | PALATIN TECHNOLOGIES INC (US) | 2021-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198201-A1 | Orally Active Melanocortin Receptor-4 Compounds | MC4R, MC1R, MC3R | GABRA1 718/4885GABRB2 974/4885MAPT 1199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.