Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334528 | 1.00 | KDM4E (0.44) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL11466995 | 0.80 | TGFBR1 (0.32) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL9410682 | 0.80 | KDM4E (0.44) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL1023967 | 0.78 | KDM4E (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL20154874 | 0.77 | FOLH1 (0.50) | NFKB1BLMFOLH1 | |
| SCHEMBL757317 | 0.77 | ECE1 (0.40) | KDM4EMAPTCA1CA2TGFBR1 | |
| SCHEMBL10355085 | 0.77 | FOLH1 (0.50) | NFKB1BLMFOLH1 | |
| SCHEMBL759008 | 0.74 | KMT2A (0.41) | ALOX15NFKB1BLMFOLH1CA1 | |
| SCHEMBL1843782 | 0.74 | KMT2A (0.41) | ALOX15NFKB1BLMFOLH1CA1 | |
| SCHEMBL3075730 | 0.74 | KDM4E (0.39) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346883-B1 | Expectorant comprising hydroxy-alkylcysteine derivative | SS PHARMACEUTICAL CO (JP) | 1994-05-18 | — | — | EP | claimed |
| EP-0346882-B1 | HYDROXYALKYLCYSTEINE DERIVATIVE AND EXPECTORANT CONTAINING THE SAME | SS PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | claimed |
| US-5047428-A | Side effect reduction | SS PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | claimed |
| US-4906665-A | Hydroxyalkylcysteine derivative and expectorant containing the same | SS PHARMACEUTICAL CO., LTD. (JP) | 1990-03-06 | — | — | US | claimed |
| EP-0346883-A2 | Expectorant comprising hydroxy-alkylcysteine derivative | SS PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | claimed |
| EP-0346882-A2 | Hydroxyalkylcysteine derivative and expectorant containing the same | SS PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | claimed |
| JP-2003674-A | — | — | None | — | — | JP | disclosed |
| EP-1391202-B1 | LIQUID DRUG PREPARATIONS | HISAMITSU PHARMACEUTICAL CO (JP) | 2011-08-03 | — | — | EP | disclosed |
| JP-2005126352-A | DIARRHEA REMEDY | MITSUBISHI PHARMA CORP | 2005-05-19 | — | — | JP | disclosed |
| EP-0998926-B1 | Oral preparation comprising S-(3-hydroxypropyl)-L-cysteine | SSP CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| EP-0346883-B1 | Expectorant comprising hydroxy-alkylcysteine derivative | SS PHARMACEUTICAL CO (JP) | 1994-05-18 | — | — | EP | disclosed |
| EP-0346882-B1 | HYDROXYALKYLCYSTEINE DERIVATIVE AND EXPECTORANT CONTAINING THE SAME | SS PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-5047428-A | Side effect reduction | SS PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| US-4906665-A | Hydroxyalkylcysteine derivative and expectorant containing the same | SS PHARMACEUTICAL CO., LTD. (JP) | 1990-03-06 | — | — | US | disclosed |
| JP-H023674-A | HYDROXYALKYLCYSTEINE DERIVATIVE AND EXPECTORANT CONTAINING THE SAME DERIVATIVE | SS PHARMACEUT CO LTD | 1990-01-09 | — | — | JP | disclosed |
| EP-0346882-A2 | Hydroxyalkylcysteine derivative and expectorant containing the same | SS PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | disclosed |
| EP-0346883-A2 | Expectorant comprising hydroxy-alkylcysteine derivative | SS PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | disclosed |
| EP-0346882-A2 | Hydroxyalkylcysteine derivative and expectorant containing the same | SS PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | disclosed |
| EP-0346883-A2 | Expectorant comprising hydroxy-alkylcysteine derivative | SS PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | disclosed |
| EP-0346882-A2 | Hydroxyalkylcysteine derivative and expectorant containing the same | SS PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | disclosed |