SCHEMBL2358802

SCHEMBL2358802

C[C@@]1(C(=O)O)C[C@H](N)CN1C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15720287 1.00 APLNR (0.30) APLNR
SCHEMBL17237788 1.00 APLNR (0.30) APLNR
Hydrochloric Acid SCHEMBL28283600 0.81 MMP2 (0.31)
SCHEMBL376556 0.79 NR1H2 (0.37)
SCHEMBL1267010 0.79 NR1H2 (0.37)
SCHEMBL1922848 0.79 NR1H2 (0.37)
SCHEMBL1266908 0.79 NR1H2 (0.37)
SCHEMBL19463058 0.78 APLNR (0.31) APLNR
SCHEMBL17237784 0.78 APLNR (0.31) APLNR
SCHEMBL1924641 0.78 APLNR (0.31) APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011092671-A1 PROLINE DERIVATIVES FOR USE IN THE TREATMENT OF DIABETES RANBAXY LABORATORIES LIMITED (IN) 2011-08-04 WO disclosed