SCHEMBL235883

SCHEMBL235883

COc1ccc(C=Cc2ccccc2)c(OC)c1OC

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 7/20 0.75
CYP19A1 P11511 2/20 0.71
CYP1A1 P04798 6/20 0.68
CYP1B1 Q16678 6/20 0.68
TRPA1 O75762 1/20 0.62
TUBB1 Q9H4B7 2/20 0.61
TUBB4A P04350 1/20 0.61
TUBB P07437 1/20 0.61
TUBA3C P0DPH7 1/20 0.61
TUBA1B P68363 1/20 0.61
TUBA4A P68366 1/20 0.61
TUBB4B P68371 1/20 0.61
TUBB3 Q13509 1/20 0.61
TUBB2A Q13885 1/20 0.61
TUBB8 Q3ZCM7 1/20 0.61
TUBA3E Q6PEY2 1/20 0.61
TUBA1A Q71U36 1/20 0.61
TUBA1C Q9BQE3 1/20 0.61
TUBB6 Q9BUF5 1/20 0.61
TUBB2B Q9BVA1 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5497353 1.00 NFE2L2 (0.75) NFE2L2CYP19A1CYP1A1CYP1B1TRPA1
SCHEMBL1603723 0.86 NFE2L2 (1.00) NFE2L2CYP19A1CYP1A1CYP1B1TRPA1
SCHEMBL5500710 0.86 NFE2L2 (1.00) NFE2L2CYP19A1CYP1A1CYP1B1TRPA1
SCHEMBL3937908 0.85 NFE2L2 (0.56) NFE2L2CYP19A1CYP1A1CYP1B1TRPA1
SCHEMBL27882842 0.85 NFE2L2 (0.64) NFE2L2CYP19A1CYP1A1CYP1B1TRPA1
SCHEMBL27651551 0.85 NFE2L2 (0.64) NFE2L2CYP19A1CYP1A1CYP1B1TRPA1
SCHEMBL9190919 0.84 CYP19A1 (0.73) NFE2L2CYP19A1CYP1A1CYP1B1TUBB1
SCHEMBL5494173 0.84 CYP19A1 (0.73) NFE2L2CYP19A1CYP1A1CYP1B1TUBB1
SCHEMBL5494166 0.84 CYP19A1 (0.73) NFE2L2CYP19A1CYP1A1CYP1B1TUBB1
SCHEMBL29136488 0.84 TUBB1 (0.69) NFE2L2CYP19A1CYP1A1CYP1B1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4229216-B1 DETECTION AND ANALYSIS OF STRUCTURAL VARIATIONS IN GENOMES UNIV LELAND STANFORD JUNIOR (US) 2026-04-22 EP claimed
US-20250346951-A1 METHODS FOR AMPLIFYING POLYNUCLEOTIDE SEQUENCES IN SITU Singular Genomics Systems, Inc. 2025-11-13 US claimed
US-12391988-B2 Sequencing a target sequence in a cell Singular Genomics Systems, Inc. (US) 2025-08-19 US claimed
US-20250115958-A1 METHODS FOR DETECTING POLYNUCLEOTIDE SEQUENCES IN SITU FIRST-CITIZENS BANK & TRUST COMPANY 2025-04-10 US claimed
US-12091660-B2 Detection and analysis of structural variations in genomes THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-09-17 US claimed
EP-4427758-A1 NEW SYNERGISTIC ANTI-INFLAMMATORY, ANTIOXIDANT AND ANTIBACTERIAL ASSOCIATION NOOS S.r.l. (IT) 2024-09-11 EP claimed
US-20240271208-A1 METHODS FOR DIFFERENTIATING MODIFIED NUCLEOBASES FIRST-CITIZENS BANK & TRUST COMPANY 2024-08-15 US claimed
EP-4396339-A1 METHODS FOR DIFFERENTIATING MODIFIED NUCLEOBASES Singular Genomics Systems, Inc. (US) 2024-07-10 EP claimed
US-20240158845-A1 METHODS AND COMPOSITIONS FOR SEQUENCING COMPLEMENTARY POLYNUCLEOTIDES Singular Genomics Systems, Inc. 2024-05-16 US claimed
US-11913071-B2 Methods and compositions for sequencing complementary polynucleotides Singular Genomics Systems, Inc. (US) 2024-02-27 US claimed
EP-2060255-A2 Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection The Regents Of The University Of California (US) 2009-05-20 EP claimed
WO-2009035539-A2 LONG INTERFERING NUCLEIC ACID DUPLEXES TARGETING MULTIPLE RNA TARGETS NT OMICS INC. (US) 2009-03-19 WO claimed
EP-1450819-A4 METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF INFLAMMATORY DISEASE, AUTOIMMUNE DISEASE, AND TRANSPLANT REJECTION UNIV CALIFORNIA (US) 2008-01-23 EP claimed
CN-101026959-A Fungicidally active polymer dispersions and use thereof CELANESE EMULSIONS GMBH (DE) 2007-08-29 CN claimed
EP-1796459-A2 FUNGICIDALLY ACTIVE POLYMER DISPERSIONS AND USE THEREOF Celanese Emulsions GmbH (DE) 2007-06-20 EP claimed
WO-2006034762-A2 FUNGICIDALLY ACTIVE POLYMER DISPERSIONS AND USE THEREOF CELANESE EMULSIONS GMBH (DE) 2006-04-06 WO claimed
US-20040242500-A1 Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-12-02 US claimed
EP-1450819-A1 METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF INFLAMMATORY DISEASE, AUTOIMMUNE DISEASE, AND TRANSPLANT REJECTION The Regents of the University of California (US) 2004-09-01 EP claimed
WO-2003039557-A1 METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF INFLAMMATORY DISEASE, AUTOIMMUNE DISEASE, AND TRANSPLANT REJECTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-05-15 WO claimed
WO-2003031381-A2 SYNTHESIS OF (Z)-3,5,4'-TRIMETHOXYSTILBENE, AND USE THEREOF UNIVERSITE LOUIS PASTEUR (FR) 2003-04-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242500-A1 Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection TNF, HLA-DRB1, IL5 NFE2L2 730/4885CYP19A1 427/4885CYP1A1 1344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.