SCHEMBL2358864

SCHEMBL2358864

CC1(C)OB(c2cnn(C3CCOCC3)c2)OC1(C)C

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.45
LRRK2 Q5S007 4/20 0.36
MPO P05164 1/20 0.35
IRAK4 Q9NWZ3 2/20 0.35
CCNE1 P24864 3/20 0.34
CDK2 P24941 3/20 0.34
CDK1 P06493 2/20 0.34
CCNB1 P14635 2/20 0.34
MKNK1 Q9BUB5 1/20 0.34
JAK1 P23458 4/20 0.34
JAK3 P52333 4/20 0.34
JAK2 O60674 3/20 0.34
ALK Q9UM73 2/20 0.34
TYK2 P29597 1/20 0.33
EIF2AK4 Q9P2K8 1/20 0.33
MAPK1 P28482 1/20 0.33
EML4 Q9HC35 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21588687 0.92 FFAR1 (0.40) FFAR1LRRK2IRAK4CCNE1CDK2
SCHEMBL18010602 0.92 FFAR1 (0.43) FFAR1LRRK2MPOIRAK4MKNK1
SCHEMBL1954029 0.92 FFAR1 (0.43) FFAR1LRRK2MPOIRAK4MKNK1
SCHEMBL17102316 0.92 FFAR1 (0.43) FFAR1LRRK2MPOIRAK4MKNK1
SCHEMBL1987497 0.91 FFAR1 (0.49) FFAR1LRRK2MPOIRAK4JAK1
SCHEMBL21588746 0.91 FFAR1 (0.40) FFAR1LRRK2MPOIRAK4CCNE1
SCHEMBL2572488 0.88 FFAR1 (0.47) FFAR1LRRK2MPOIRAK4JAK1
SCHEMBL2517121 0.88 FFAR1 (0.47) FFAR1MPOIRAK4JAK1JAK3
SCHEMBL2749177 0.87 FFAR1 (0.46) FFAR1MPOIRAK4CCNE1CDK2
SCHEMBL17801242 0.87 FFAR1 (0.46) FFAR1MPOIRAK4CCNE1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113248437-B Tetraphenyl vinyl poly-pyrazole nitrogen-containing heterocyclic compound and preparation method and application thereof 北京工业大学 2022-11-18 CN claimed
CN-113248437-A Tetraphenyl vinyl poly-pyrazole nitrogen-containing heterocyclic compound and preparation method and application thereof 北京工业大学 2021-08-13 CN claimed
CN-113201142-A Hydrogen bond organic grid material based on aromatic tetrapyrazole and preparation method and application thereof 北京工业大学 2021-08-03 CN claimed
CN-109456309-B Multi-pyrazole nitrogen-containing heterocyclic compound and preparation and application thereof 北京工业大学 2020-11-27 CN claimed
US-20260138986-A1 PYRROLOTRIAZINE DERIVATIVES FOR TREATING KIT- AND PDGFRA-MEDIATED DISEASES BLUEPRINT MEDICINES CORP (US) 2026-05-21 US disclosed
WO-2026102563-A1 DISUBSTITUTED PYRIMIDOPYRROLE ANALOG AND USE THEREOF 深圳湾实验室坪山生物医药研发转化中心 2026-05-21 WO disclosed
EP-4724431-A1 BENZOFURAN DERIVATIVES AS SIK INHIBITORS AND USE THEREOF Beone Medicines I GmbH (CH) 2026-04-15 EP disclosed
US-20260098044-A1 TRICYCLIC HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2 AND/OR JAK1 INCYTE CORP (US) 2026-04-09 US disclosed
US-20260085053-A1 BENZOFURAN DERIVATIVES AS SIK INHIBITORS AND THE USE THEREOF BEONE MEDICINES I GMBH (CH) 2026-03-26 US disclosed
EP-4713095-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS Chengdu Anticancer Bioscience, Ltd. (CN) 2026-03-25 EP disclosed
US-12552804-B2 Tricyclic heterocycles as FGFR inhibitors INCYTE CORPORATION (US) 2026-02-17 US disclosed
US-20250353842-A1 BICYCLIC AMINE CDK12 INHIBITORS INCYTE CORP (US) 2025-11-20 US disclosed
WO-2010048131-A1 C-MET PROTEIN KINASE INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-04-29 WO disclosed
WO-2010048131-A1 C-MET PROTEIN KINASE INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-04-29 WO disclosed
US-20100063031-A1 KINASE INHIBITOR COMPOUNDS XCOVERY, INC. (US) 2010-03-11 US disclosed
US-20100063031-A1 KINASE INHIBITOR COMPOUNDS XCOVERY, INC. (US) 2010-03-11 US disclosed
US-20090215776-A1 Organic compounds ADCOCK CLAIRE 2009-08-27 US disclosed
WO-2009087212-A2 PYRIDINE DERIVATIVES NOVARTIS AG (CH) 2009-07-16 WO disclosed
WO-2009024825-A1 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS ASTRAZENECA AB (SE) 2009-02-26 WO disclosed
WO-2008148867-A2 QUINOXALINE DERIVATIVES AS INHIBITORS OF THE TYROSINE KINASE ACTIVITY OF JANUS KINASES NOVARTIS AG (CH) 2008-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085053-A1 BENZOFURAN DERIVATIVES AS SIK INHIBITORS AND THE USE THEREOF SIK1, CHUK, SIK2 FFAR1 1410/4885LRRK2 1045/4885MPO 1542/4885
US-20090215776-A1 Organic compounds REN, RXFP1, MYLK FFAR1 256/4885LRRK2 2666/4885MPO 319/4885
US-20100063031-A1 KINASE INHIBITOR COMPOUNDS MAP4K2, MAP3K5, MAP3K15 FFAR1 4647/4885LRRK2 445/4885MPO 4680/4885
US-20250353842-A1 BICYCLIC AMINE CDK12 INHIBITORS CDK12, CDK1, CDK2 FFAR1 4858/4885LRRK2 447/4885MPO 4315/4885
US-12552804-B2 Tricyclic heterocycles as FGFR inhibitors FGFR3, FGFR1, FGFR2 FFAR1 1016/4885LRRK2 779/4885MPO 4382/4885
US-20260138986-A1 PYRROLOTRIAZINE DERIVATIVES FOR TREATING KIT- AND PDGFRA-MEDIATED DISEASES KIT, PDGFRA, PDGFRB FFAR1 766/4885LRRK2 278/4885MPO 2312/4885
US-20260098044-A1 TRICYCLIC HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2 AND/OR JAK1 JAK1, TYK2, JAK2 FFAR1 452/4885LRRK2 261/4885MPO 3638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.