Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.66 |
| ▸ | WNT3A | P56704 | 3/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2379710 | 0.83 | CTNNB1 (0.66) | CTNNB1WNT3AATMSMYD3HPGD | |
| SCHEMBL11441068 | 0.82 | CTNNB1 (0.64) | CTNNB1WNT3ASMYD3HPGD | |
| SCHEMBL15980036 | 0.81 | CTNNB1 (0.76) | CTNNB1WNT3ASMYD3HPGDTSHR | |
| SCHEMBL13516290 | 0.81 | CTNNB1 (0.56) | CTNNB1WNT3AATMSMYD3MRGPRX4 | |
| SCHEMBL18641649 | 0.81 | CTNNB1 (0.67) | CTNNB1WNT3ASMYD3MRGPRX4MAPT | |
| SCHEMBL1347343 | 0.81 | CTNNB1 (0.58) | CTNNB1WNT3ASMYD3MRGPRX4MAPT | |
| SCHEMBL10407674 | 0.80 | CTNNB1 (0.61) | CTNNB1WNT3ASMYD3MRGPRX4MAPT | |
| SCHEMBL23209151 | 0.80 | CTNNB1 (0.61) | CTNNB1WNT3AATMSMYD3HPGD | |
| SCHEMBL15969201 | 0.80 | CTNNB1 (1.00) | CTNNB1WNT3ASMYD3MRGPRX4TSHR | |
| SCHEMBL29214587 | 0.80 | CTNNB1 (0.54) | CTNNB1WNT3ASMYD3MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326749-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS INC (US) | 2025-10-23 | — | — | US | disclosed |
| EP-4536655-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | Sionna Therapeutics Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-119677730-A | Compounds, compositions, and methods of use thereof | 希安纳医疗公司 | 2025-03-21 | — | — | CN | disclosed |
| WO-2023240267-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023240267-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2023-12-14 | — | — | WO | disclosed |
| US-10017508-B2 | Nitrogenated heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-07-10 | — | — | US | disclosed |
| EP-2848618-B1 | NITROGENATED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2018-03-14 | — | — | EP | disclosed |
| US-20170129887-A1 | NITROGENATED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2017-05-11 | — | — | US | disclosed |
| US-9469637-B2 | Nitrogenated heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-10-18 | — | — | US | disclosed |
| US-20150105373-A1 | NITROGENATED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-04-16 | — | — | US | disclosed |
| EP-2848618-A1 | NITROGENATED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-03-18 | — | — | EP | disclosed |
| EP-2349966-A1 | NEW ANALOGS OF POLYSPHORIN AND USES THEREOF FOR TREATING OR PREVENTING MALARIA | Assistance Publique - Hôpitaux de Paris (FR) | 2011-08-03 | — | — | EP | disclosed |
| EP-2177496-A1 | New analogs of polysphorin and uses thereof for treating or preventing malaria | Assistance Publique - Hopitaux de Paris (FR) | 2010-04-21 | — | — | EP | disclosed |
| EP-2177496-A1 | New analogs of polysphorin and uses thereof for treating or preventing malaria | Assistance Publique - Hopitaux de Paris (FR) | 2010-04-21 | — | — | EP | disclosed |
| WO-2010040730-A1 | NEW ANALOGS OF POLYSPHORIN AND USES THEREOF FOR TREATING OR PREVENTING MALARIA | ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS (FR) | 2010-04-15 | — | — | WO | disclosed |
| EP-0424125-A2 | Aralkylamine derivatives, preparation method thereof and fungicides containing the same | UBE INDUSTRIES, LTD. (JP) | 1991-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105373-A1 | NITROGENATED HETEROCYCLIC COMPOUND | PDE2A, PDE5A, PDE3A | CTNNB1 1484/4885WNT3A 3188/4885ATM 3251/4885 |
| US-20250326749-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | CFTR, SLC26A4, PKD2 | CTNNB1 1966/4885WNT3A 1706/4885ATM 2116/4885 |
| US-20170129887-A1 | NITROGENATED HETEROCYCLIC COMPOUND | PDE2A, PDE5A, PDE3A | CTNNB1 1484/4885WNT3A 3188/4885ATM 3251/4885 |
| US-10017508-B2 | Nitrogenated heterocyclic compound | PDE2A, PDE5A, PDE3A | CTNNB1 1484/4885WNT3A 3188/4885ATM 3251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.