Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 15/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10204343 | 0.90 | NAMPT (0.50) | NAMPTPIK3CDHPGD | |
| SCHEMBL10204342 | 0.83 | NAMPT (0.50) | NAMPTPIK3CDHPGD | |
| SCHEMBL1458106 | 0.80 | HPGD (0.48) | NAMPTHPGD | |
| SCHEMBL10204341 | 0.79 | CKS1B (0.57) | NAMPTHPGD | |
| SCHEMBL1458676 | 0.77 | NAMPT (0.52) | NAMPTHPGD | |
| SCHEMBL1458701 | 0.76 | HPGD (0.52) | NAMPTHPGD | |
| SCHEMBL10204327 | 0.75 | HPGD (0.47) | NAMPTHPGD | |
| SCHEMBL1458722 | 0.75 | HPGD (0.50) | NAMPTHPGD | |
| SCHEMBL1458738 | 0.75 | CKS1B (0.52) | NAMPTHPGD | |
| SCHEMBL1459727 | 0.74 | HPGD (0.53) | NAMPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198216-A1 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | BIOENERGENIX LLC (US) | 2021-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198216-A1 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | PASK, PDXK, PANK2 | NAMPT 544/4885PIK3CD 648/4885HPGD 824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.