SCHEMBL235895

SCHEMBL235895

CC(C)C[Si](NC(C)C)(NC(C)C)NC1CCCC1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.34
EPHX1 P07099 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234677 0.75
SCHEMBL232293 0.72 ALDH1A1 (0.33) HTTEPHX1ALDH1A1GAA
SCHEMBL234434 0.72 ALDH1A1 (0.33) HTTEPHX1ALDH1A1GAA
SCHEMBL236464 0.70 ALDH1A1 (0.38) EPHX1ALDH1A1CYP3A4GAARAB9A
SCHEMBL234949 0.70 ALDH1A1 (0.38) EPHX1ALDH1A1CYP3A4GAARAB9A
SCHEMBL231545 0.69 ALDH1A1 (0.35) EPHX1ALDH1A1
SCHEMBL235396 0.68 ALDH1A1 (0.31) ALDH1A1GAA
SCHEMBL236233 0.67 ALDH1A1 (0.39) EPHX1ALDH1A1
SCHEMBL233866 0.67
SCHEMBL236287 0.65 ALDH1A1 (0.33) EPHX1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed