Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21888966 | 0.77 | GAA (0.62) | GAASMN1; SMN2MAPK1KMT2AHSD17B10 | |
| SCHEMBL1994355 | 0.73 | GAA (1.00) | GAAALDH1A1HTTPIK3R1PIK3CA | |
| SCHEMBL22761364 | 0.70 | GAA (0.54) | GAASMN1; SMN2MAPK1KMT2AHSD17B10 | |
| SCHEMBL22750817 | 0.69 | GAA (0.62) | GAASMN1; SMN2MAPK1HSD17B10POLB | |
| SCHEMBL8973821 | 0.68 | HTT (0.63) | GAASMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL2815267 | 0.67 | MAPK1 (0.51) | GAASMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL9418611 | 0.66 | HTT (0.61) | GAASMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL12110270 | 0.66 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPK1KMT2AMEN1NUDT1 | |
| SCHEMBL15386251 | 0.64 | MAPT (0.50) | GAASMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL17827961 | 0.64 | PIK3CA (0.51) | SMN1; SMN2MAPK1ALDH1A1PIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198220-A1 | SSAO INHIBITOR | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198220-A1 | SSAO INHIBITOR | SSB, ASAH2, AOX1 | GAA 51/4885SMN1; SMN2 1539/4885MAPK1 3164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.