Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.55 |
| ▸ | MTOR | P42345 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973821 | 0.97 | HTT (0.63) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL28641102 | 0.85 | HTT (0.53) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL9619196 | 0.85 | KDM4E (0.58) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL1308905 | 0.85 | MAPT (0.61) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL1443593 | 0.85 | PIK3CA (0.61) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL30702225 | 0.84 | PIK3CA (0.59) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL778162 | 0.84 | HRH1 (0.65) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL11364292 | 0.84 | HTT (0.61) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL778143 | 0.84 | HRH1 (0.65) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL6740206 | 0.83 | LMNA (0.70) | HTTKDM4ELMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116891-A | Bistriazinylpiperazine and ammonium polyphosphate mixtures with olefin polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | claimed |
| EP-0441134-A2 | Flame retardant polymeric compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-14 | — | — | EP | claimed |
| EP-0441135-B1 | Selfextinguishing polyurethanes | HOECHST AG (DE) | 1994-10-05 | — | — | EP | disclosed |
| US-5116891-A | Bistriazinylpiperazine and ammonium polyphosphate mixtures with olefin polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| US-5099017-A | N,N'-BIS-1,3,5-TRIAZIN-6-YLPIPERAZINES, AND PROCESSES FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-24 | — | — | US | disclosed |
| US-5096961-A | Ammonium polyphosphate and bis/triazinyl/piperazine as fireproofing synergist | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| EP-0441135-A2 | Selfextinguishing polyurethanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-14 | — | — | EP | disclosed |
| EP-0441134-A2 | Flame retardant polymeric compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-14 | — | — | EP | disclosed |