Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 7/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444693 | 0.80 | BRD4 (0.58) | MAPTGAAL3MBTL1PPIA | |
| SCHEMBL23592014 | 0.80 | SLC1A5 (0.47) | POLBMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL29824416 | 0.80 | BRD4 (0.67) | POLBMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL25426801 | 0.80 | BRD4 (0.67) | POLBMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL23591751 | 0.80 | L3MBTL1 (0.50) | POLBMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL29824938 | 0.80 | L3MBTL1 (0.50) | POLBMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL38660470 | 0.78 | MRGPRX4 (0.62) | ALDH1A1GAAL3MBTL1NR4A2MAOB | |
| SCHEMBL18003390 | 0.75 | POLB (0.60) | POLBMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL12330828 | 0.75 | FFAR4 (0.60) | MAPTALDH1A1GAAL3MBTL1NR4A2 | |
| SCHEMBL23592013 | 0.75 | MAOB (0.62) | ALDH1A1GAAL3MBTL1NR4A2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133896-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-07-01 | — | — | WO | disclosed |