Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23591877 | 0.83 | IDH2 (0.46) | POLBMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL23592012 | 0.80 | POLB (0.50) | SLC1A5POLBMAPTALDH1A1GAA | |
| SCHEMBL29824938 | 0.78 | L3MBTL1 (0.50) | SLC1A5POLBMAPTALDH1A1GAA | |
| SCHEMBL23591751 | 0.78 | L3MBTL1 (0.50) | SLC1A5POLBMAPTALDH1A1GAA | |
| SCHEMBL29824416 | 0.76 | BRD4 (0.67) | POLBMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL25426801 | 0.76 | BRD4 (0.67) | POLBMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL38660470 | 0.74 | MRGPRX4 (0.62) | ALDH1A1GAAL3MBTL1NR4A2MAOB | |
| SCHEMBL10856962 | 0.72 | MAOB (0.58) | SLC1A5POLBMAPTALDH1A1GAA | |
| SCHEMBL7564964 | 0.72 | IDO1 (0.49) | POLBMAPTL3MBTL1NR4A2MAOB | |
| SCHEMBL21294760 | 0.71 | ACP3 (0.51) | POLBMAPTALDH1A1MAOBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133896-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-07-01 | — | — | WO | disclosed |