Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23592444 | 1.00 | RECQL (0.48) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL23581717 | 0.83 | PDK1 (0.40) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL23581716 | 0.83 | PDK1 (0.40) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL30230188 | 0.82 | KDM4E (0.49) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL23592622 | 0.80 | RECQL (0.59) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL17749330 | 0.80 | RECQL (0.59) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL17749375 | 0.78 | SMN1; SMN2 (0.50) | RECQLSMN1; SMN2KDM4ETHRBPKM | |
| SCHEMBL29878090 | 0.78 | RECQL (0.53) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL8140489 | 0.78 | PDK1 (0.54) | RECQLUSP2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL17897027 | 0.78 | PDK1 (0.54) | RECQLUSP2SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829345-A | Acylsulfonamide compound and medicinal use thereof | 日本烟草产业株式会社 | 2022-07-29 | — | — | CN | disclosed |
| WO-2021132577-A1 | ACYLSULFAMIDE COMPOUND AND PHARMACEUTICAL USE THEREFOR | 日本たばこ産業株式会社 | 2021-07-01 | — | — | WO | disclosed |