Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17749330 | 1.00 | RECQL (0.59) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL8904969 | 0.87 | USP2 (0.53) | RECQLUSP2SMN1; SMN2HPGDNR1H2 | |
| SCHEMBL304803 | 0.87 | USP2 (0.53) | RECQLUSP2SMN1; SMN2HPGDNR1H2 | |
| SCHEMBL304804 | 0.87 | USP2 (0.53) | RECQLUSP2SMN1; SMN2HPGDNR1H2 | |
| SCHEMBL553919 | 0.87 | USP2 (0.53) | RECQLUSP2SMN1; SMN2HPGDNR1H2 | |
| SCHEMBL29878090 | 0.86 | RECQL (0.53) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL29864929 | 0.84 | RECQL (0.49) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL23592444 | 0.80 | RECQL (0.48) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL23592445 | 0.80 | RECQL (0.48) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL23380189 | 0.80 | RECQL (0.60) | RECQLUSP2SMN1; SMN2HPGDEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399319-A1 | Acylsulfamide Compound and Pharmaceutical Use Therefor | JAPAN TOBACCO INC. (JP) | 2023-12-14 | — | — | US | disclosed |
| US-20230399319-A1 | Acylsulfamide Compound and Pharmaceutical Use Therefor | JAPAN TOBACCO INC. (JP) | 2023-12-14 | — | — | US | disclosed |
| US-20230399319-A1 | Acylsulfamide Compound and Pharmaceutical Use Therefor | JAPAN TOBACCO INC. (JP) | 2023-12-14 | — | — | US | disclosed |
| EP-4082614-A1 | ACYLSULFAMIDE COMPOUND AND PHARMACEUTICAL USE THEREFOR | Japan Tobacco Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |
| CN-114829345-A | Acylsulfonamide compound and medicinal use thereof | 日本烟草产业株式会社 | 2022-07-29 | — | — | CN | disclosed |
| WO-2021132577-A1 | ACYLSULFAMIDE COMPOUND AND PHARMACEUTICAL USE THEREFOR | 日本たばこ産業株式会社 | 2021-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399319-A1 | Acylsulfamide Compound and Pharmaceutical Use Therefor | NLRP3, NLRP1, NOD1 | RECQL 2407/4885USP2 2879/4885SMN1; SMN2 4777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.