⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10274503 | 0.73 | — | — | |
| SCHEMBL11466443 | 0.73 | — | — | |
| SCHEMBL4351043 | 0.69 | POLB (0.37) | — | |
| SCHEMBL2359396 | 0.67 | — | — | |
| SCHEMBL5275675 | 0.67 | MAPT (0.31) | — | |
| SCHEMBL10790381 | 0.65 | — | — | |
| SCHEMBL24045039 | 0.60 | KDM4E (0.36) | — | |
| SCHEMBL9478647 | 0.59 | NPC1 (0.33) | — | |
| SCHEMBL13208398 | 0.59 | RXFP1 (0.34) | — | |
| SCHEMBL24045022 | 0.56 | LMNA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612094-B2 | Tri-substituted heteroaryls and methods of making and using the same | BIOGEN IDEC MA INC. (US) | 2009-11-03 | — | — | US | claimed |
| EP-1804801-A2 | METHODS OF TREATING VASCULAR INJURIES | Biogen Idec MA, Inc. (US) | 2007-07-11 | — | — | EP | claimed |
| WO-2006044509-A2 | METHODS OF TREATING VASCULAR INJURIES | BIOGEN IDEC MA INC. (US) | 2006-04-27 | — | — | WO | claimed |
| US-20060063809-A1 | Tri-substituted heteroaryls and methods of making and using the same | BIOGEN MA INC. | 2006-03-23 | — | — | US | claimed |
| EP-1499308-A2 | TRI-SUBSTITUTED HETEROARYLS AND METHODS OF MAKING AND USING THE SAME | BIOGEN, INC. (US) | 2005-01-26 | — | — | EP | claimed |
| US-20040110778-A1 | Heterocyclic compounds as ligands of the GABAA receptor | YOHANNES DANIEL (US) | 2004-06-10 | — | — | US | claimed |
| WO-2003087304-A2 | TRI-SUBSTITUTED HETEROARYLS AND METHODS OF MAKING AND USING THE SAME | BIOGEN, INC. (US) | 2003-10-23 | — | — | WO | claimed |
| EP-1325006-A2 | HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABA A? RECEPTOR | NEUROGEN CORPORATION (US) | 2003-07-09 | — | — | EP | claimed |
| US-20030105081-A1 | Heterocyclic compounds as ligands of the GABAA receptor | PFIZER INC | 2003-06-05 | — | — | US | claimed |
| WO-2002012442-A2 | HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABAA RECEPTOR | NEUROGEN CORPORATION (US) | 2002-02-14 | — | — | WO | claimed |
| US-20190330192-A1 | SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-10-31 | — | — | US | disclosed |
| US-20170340633-A1 | INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA | ICOS CORPORATION | 2017-11-30 | — | — | US | disclosed |
| CN-106699676-A | Preparation method of 3-amino-1-methyl-5-methylthio-1,2,4-triazole | 宁夏蓝博思化学技术有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-106699676-A | Preparation method of 3-amino-1-methyl-5-methylthio-1,2,4-triazole | 宁夏蓝博思化学技术有限公司 | 2017-05-24 | — | — | CN | disclosed |
| US-20170049772-A1 | INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA | ICOS CORPORATION | 2017-02-23 | — | — | US | disclosed |
| EP-0073562-B1 | HERBICIDAL TRIAZOLE UREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-09 | — | — | EP | disclosed |
| EP-0103537-B1 | N-ARYLSULFONYL-N'-TRIAZOLYL UREA | CIBA-GEIGY AG (CH) | 1987-07-08 | — | — | EP | disclosed |
| EP-0103537-A2 | N-arylsulfonyl-N'-triazolyl urea | CIBA-GEIGY AG (CH) | 1984-03-21 | — | — | EP | disclosed |
| US-4421550-A | PRE- AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-12-20 | — | — | US | disclosed |
| EP-0073562-A2 | Herbicidal triazole ureas | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-03-09 | — | — | EP | disclosed |