SCHEMBL2359485

SCHEMBL2359485

C=CC(=O)OCCC(OC(C)C)[SiH](C)C

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.44
HPGD P15428 1/20 0.43
ALDH1A1 P00352 4/20 0.43
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
CYP3A4 P08684 2/20 0.43
HSD17B10 Q99714 1/20 0.43
THRB P10828 2/20 0.41
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28686220 0.83 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL374777 0.81 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9103359 0.75 TSHR (0.57) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL34661 0.75 TSHR (0.63) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL29550542 0.75 TSHR (0.63) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL17922840 0.73 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL142522 0.73 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27800524 0.73 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8660776 0.73 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A
Ethylene SCHEMBL28783854 0.73 TSHR (0.61) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507622-B2 Polymerizable compositions ROHM AND HAAS COMPANY (US) 2013-08-13 US disclosed
EP-2236527-B1 Improved polymerizable compostions ROHM & HAAS (US) 2011-08-17 EP disclosed
EP-2236528-B1 Improved polymerizable compositions ROHM & HAAS (US) 2011-08-03 EP disclosed
EP-2236527-A1 Improved polymerizable compostions Rohm and Haas Company (US) 2010-10-06 EP disclosed
EP-2236528-A1 Improved polymerizable compositions Rohm and Haas Company (US) 2010-10-06 EP disclosed
US-20100249365-A1 Polymerizable compositions LEMONDS ANDREW 2010-09-30 US disclosed
US-20100249348-A1 Polymerizable compositions ROHM AND HAAS COMPANY 2010-09-30 US disclosed
US-6566549-B1 Forming oligomers of vinyl acetate and oligomers of vinyl alcohol; fully saturated and terminally unsaturated oligomers ROHM AND HAAS COMPANY 2003-05-20 US disclosed
US-20020111448-A1 Continuous polymerization process and products therefrom GREENBLATT GARY DAVID (US) 2002-08-15 US disclosed
US-20020082371-A1 Continuous polymerization process and products therefrom GREENBLATT GARY DAVID (US) 2002-06-27 US disclosed
EP-1010706-A2 Continuous polymerization process and products therefrom ROHM AND HAAS COMPANY (US) 2000-06-21 EP disclosed