SCHEMBL374777

SCHEMBL374777

C=CC(=O)OCCC(O[Si](C)(C)C)[SiH](C)C

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.43
HPGD P15428 1/20 0.43
ALDH1A1 P00352 4/20 0.43
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
CYP3A4 P08684 2/20 0.43
HSD17B10 Q99714 1/20 0.43
THRB P10828 2/20 0.37
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2359485 0.81 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28006720 0.77 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL13966307 0.74 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5838729 0.74 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27800524 0.73 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL142522 0.73 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27800526 0.73 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5839203 0.72 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2969510 0.72 TSHR (0.52) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL933009 0.71 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1425321-A2 BEADED POLYETHYLENE GLYCOL-BASED RESINS Carlsberg A/S (DK) 2004-06-09 EP claimed
WO-2003025039-A2 BEADED POLYETHYLENE GLYCOL-BASED RESINS CARLSBERG A/S (DK) 2003-03-27 WO claimed
US-20030050415-A1 Beaded polyethylene glycol-based resins CARLSBERG A/S (DK) 2003-03-13 US claimed
EP-2128865-B1 Optical recording composition, holographic recording medium, and method of recording and reproducing information FUJIFILM CORP (JP) 2012-02-29 EP disclosed
EP-2065890-B1 Optical recording composition and holographic recording medium FUJIFILM CORP (JP) 2012-01-25 EP disclosed
US-7977015-B2 Polymerizable compound, optical recording composition, holographic recording medium and method of recording information FUJIFILM CORPORATION (JP) 2011-07-12 US disclosed
US-7835249-B2 Optical recording method, optical recording apparatus, optical recording medium, optical reproducing method, and optical reproducing apparatus FUJIFILM CORPORATION (JP) 2010-11-16 US disclosed
US-7742380-B2 Optical recording method, optical recording apparatus and optical recording medium FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-20090297955-A1 OPTICAL RECORDING COMPOSITION, HOLOGRAPHIC RECORDING MEDIUM, AND METHOD OF RECORDING AND REPRODUCING INFORMATION FUJIFILM CORPORATION (JP) 2009-12-03 US disclosed
EP-2128865-A2 Optical recording composition, holographic recording medium, and method of recording and reproducing information FUJIFILM Corporation (JP) 2009-12-02 EP disclosed
US-7626913-B2 Optical information recording method, optical information recording apparatus and optical information recording medium FUJI PHOTO FILM CO., LTD. (JP) 2009-12-01 US disclosed
US-6638991-B2 Lens material comprising a copolymer derived from a polysiloxane endcapped with acrylated urethane groups, a silicon-containing alkyl methacrylate, a hydrophilic monomer, and a crosslinking monomer; oxygen permeability, strength MENICON CO., LTD. (JP) 2003-10-28 US disclosed
US-20020198280-A1 Material for ocular lens MENICON CO., LTD. (JP) 2002-12-26 US disclosed
EP-1197782-A1 MATERIAL FOR OCULAR LENS MENICON CO., LTD. (JP) 2002-04-17 EP disclosed
US-6255362-B1 HYDRATED, CROSSLINKED COPOLYACRYLATE CONTAINING SILOXANE, URETHANE AND ETHER GROUPS; CLEAR, DURABLE, FLEXIBLE SOFT CONTACT LENSES MENICON CO., LTD. (JP) 2001-07-03 US disclosed
US-6165648-A Holographic recording LUCENT TECHNOLOGIES INC. (US) 2000-12-26 US disclosed
EP-0824222-B1 Photorecording medium and method LUCENT TECHNOLOGIES INC (US) 2000-10-18 EP disclosed
EP-0937998-A2 Ocular lens material and process for producing the same Menicon Co., Ltd. (JP) 1999-08-25 EP disclosed
US-5874187-A Photo recording medium LUCENT TECHNOLOGIES INCORPORATED (US) 1999-02-23 US disclosed
EP-0824222-A1 Photo recording medium LUCENT TECHNOLOGIES INC. (US) 1998-02-18 EP disclosed