⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3473157 | 0.75 | — | — | |
| SCHEMBL1310392 | 0.70 | — | — | |
| SCHEMBL1308722 | 0.66 | — | — | |
| SCHEMBL1310396 | 0.65 | ALDH1A1 (0.46) | — | |
| SCHEMBL197685 | 0.64 | — | — | |
| SCHEMBL13819397 | 0.64 | — | — | |
| SCHEMBL1325767 | 0.63 | ADH1B (0.34) | — | |
| SCHEMBL369085 | 0.61 | — | — | |
| SCHEMBL4740218 | 0.60 | — | — | |
| SCHEMBL29603968 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350036-B1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-04-15 | — | — | EP | disclosed |
| EP-2350036-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | Pierre Fabre Dermo-Cosmétique (FR) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010034827-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-04-01 | — | — | WO | disclosed |