Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 8/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896146 | 0.82 | HTR2A (0.49) | KDM1ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL28294840 | 0.80 | KDM1A (0.51) | KDM1ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL2320349 | 0.79 | SLC6A2 (0.41) | KDM1AABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL23993641 | 0.77 | KDM1A (0.51) | KDM1ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL2359698 | 0.75 | KDM1A (0.46) | KDM1ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL25004990 | 0.75 | KDM1A (0.46) | KDM1ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL23227588 | 0.75 | HTR2C (0.49) | KDM1ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL2326671 | 0.74 | SLC6A2 (0.42) | KDM1ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL23961571 | 0.74 | ADRA2A (0.38) | KDM1ACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL21996099 | 0.74 | ADRA2A (0.38) | KDM1ACHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |