SCHEMBL23596998

SCHEMBL23596998

Cc1c(I)ccc2ncccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.58
KDM4E B2RXH2 2/20 0.58
SMN1; SMN2 Q16637 3/20 0.49
CYP3A4 P08684 1/20 0.47
HSP90AA1 P07900 3/20 0.47
NPC1 O15118 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
LMNA P02545 4/20 0.46
HTT P42858 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
HIF1A Q16665 2/20 0.46
HSP90AB1 P08238 1/20 0.46
BLM P54132 1/20 0.46
CYP1A2 P05177 1/20 0.41
CYP1B1 Q16678 1/20 0.41
ALDH1A1 P00352 4/20 0.41
ERN1 O75460 1/20 0.40
NCOA1 Q15788 2/20 0.39
ACVR1 Q04771 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11526779 0.79 MAPT (0.62) MAPTKDM4ESMN1; SMN2CYP3A4HSP90AA1
SCHEMBL826577 0.79 MAPT (0.62) MAPTKDM4ESMN1; SMN2CYP3A4HSP90AA1
SCHEMBL13692757 0.76 MAPT (0.58) MAPTKDM4ESMN1; SMN2CYP3A4HSP90AA1
SCHEMBL5547970 0.76 MAPT (0.58) MAPTKDM4ESMN1; SMN2CYP3A4HSP90AA1
SCHEMBL18070695 0.76 MAPT (0.58) MAPTKDM4ESMN1; SMN2CYP3A4HSP90AA1
SCHEMBL23022292 0.76 MAPT (0.58) MAPTKDM4ESMN1; SMN2CYP3A4HSP90AA1
SCHEMBL5547974 0.76 KDM4E (0.58) MAPTKDM4ESMN1; SMN2CYP3A4HSP90AA1
SCHEMBL3341425 0.76 MAPT (0.71) MAPTKDM4ESMN1; SMN2CYP3A4HSP90AA1
SCHEMBL22025879 0.76 MAPT (0.58) MAPTKDM4ESMN1; SMN2CYP3A4HSP90AA1
SCHEMBL9654404 0.76 MAPT (0.58) MAPTKDM4ESMN1; SMN2CYP3A4HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067664-A1 Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-02-29 US disclosed
US-20210198222-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210198222-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNT1, CCNA1 MAPT 1322/4885KDM4E 4156/4885SMN1; SMN2 2274/4885
US-20240067664-A1 Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device CCND1, CCND2, DRD1 MAPT 3321/4885KDM4E 2966/4885SMN1; SMN2 3283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.