SCHEMBL826577

SCHEMBL826577

Cc1ccc2ncccc2c1C

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.62
KDM4E B2RXH2 1/20 0.62
SMN1; SMN2 Q16637 3/20 0.51
HSP90AA1 P07900 2/20 0.50
NPC1 O15118 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CYP3A4 P08684 1/20 0.50
LMNA P02545 3/20 0.49
HTT P42858 3/20 0.49
ALDH1A1 P00352 3/20 0.49
MEN1 O00255 1/20 0.48
HSP90AB1 P08238 1/20 0.48
BLM P54132 1/20 0.48
KMT2A Q03164 1/20 0.48
HIF1A Q16665 1/20 0.48
CYP1A2 P05177 2/20 0.47
CYP1B1 Q16678 1/20 0.47
PSMD14 O00487 1/20 0.46
COPS5 Q92905 1/20 0.46
SLC6A2 P23975 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5541888 0.79 MAPT (0.58) MAPTKDM4ESMN1; SMN2HSP90AA1NPC1
SCHEMBL22025879 0.79 MAPT (0.58) MAPTKDM4ESMN1; SMN2HSP90AA1NPC1
SCHEMBL3343150 0.79 LMNA (0.66) MAPTKDM4ESMN1; SMN2HSP90AA1NPC1
SCHEMBL430529 0.79 MAPT (0.58) MAPTKDM4ESMN1; SMN2HSP90AA1NPC1
SCHEMBL5541894 0.79 MAPT (0.58) MAPTKDM4ESMN1; SMN2HSP90AA1NPC1
SCHEMBL12121729 0.79 MAPT (0.58) MAPTKDM4ESMN1; SMN2HSP90AA1NPC1
SCHEMBL3580136 0.79 MAPT (0.58) MAPTKDM4ESMN1; SMN2HSP90AA1NPC1
SCHEMBL23022292 0.79 MAPT (0.58) MAPTKDM4ESMN1; SMN2HSP90AA1NPC1
SCHEMBL9654404 0.79 MAPT (0.58) MAPTKDM4ESMN1; SMN2HSP90AA1NPC1
SCHEMBL5547970 0.79 MAPT (0.58) MAPTKDM4ESMN1; SMN2HSP90AA1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067664-A1 Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-02-29 US disclosed
US-11771664-B2 Toxic aldehyde related diseases and treatment ALDEYRA THERAPEUTICS, INC. (US) 2023-10-03 US disclosed
US-11701331-B2 Toxic aldehyde related diseases and treatment ALDEYRA THERAPEUTICS, INC. (US) 2023-07-18 US disclosed
US-11691957-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-04 US disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed
CN-111517902-B Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2022-06-14 CN disclosed
EP-1857521-B2 ORGANIC ELECTRIC FIELD LIGHT EMITTING ELEMENT AND PRODUCTION THEREFOR MITSUBISHI CHEM CORP (JP) 2021-12-22 EP disclosed
US-11063228-B2 Metal-assisted delayed fluorescent emitters employing benzo-imidazo-phenanthridine and analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-07-13 US disclosed
US-5547828-A CYANINE DYES FUJI PHOTO FILM CO., LTD. (JP) 1996-08-20 US disclosed
US-5538838-A Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1996-07-23 US disclosed
US-5523203-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1996-06-04 US disclosed
US-5457022-A Support having silver halide emulsion layer containing atleast one metallocene compound; fog-free and storage stability FUJI PHOTO FILM CO., LTD. (JP) 1995-10-10 US disclosed
US-5439789-A Support having atleast one light sensitive silver halide emulsion layer and methine dye having benzoxazole nucleus with a halogen substituted benzene ring at 5-position FUJI PHOTO FILM CO., LTD. (JP) 1995-08-08 US disclosed
US-5422237-A Methine compound and silver halide photographic material comprising the same FUJI PHOTO FILM CO., LTD. (JP) 1995-06-06 US disclosed
EP-0625726-A1 Methine compound and silver halide photographic material comprising the same FUJI PHOTO FILM CO., LTD. (JP) 1994-11-23 EP disclosed
EP-0088595-B1 CYANINE DYES FOR SENSITIZING SILVER HALIDE EMULSIONS TO INFRARED RADIATION AND PHOTOGRAPHIC ELEMENTS INCLUDING THEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-09-24 EP disclosed
US-4515888-A BASED ON 5-METHYL-6-METHOXYBENZOTHIAZOLE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-07 US disclosed
EP-0088595-A2 Cyanine dyes for sensitizing silver halide emulsions to infrared radiation and photographic elements including them MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11771664-B2 Toxic aldehyde related diseases and treatment ALDH1A2, ALDH2, ALDH1A1 MAPT 1770/4885KDM4E 1890/4885SMN1; SMN2 1212/4885
US-11701331-B2 Toxic aldehyde related diseases and treatment ALDH1A2, ALDH2, ALDH1A1 MAPT 1770/4885KDM4E 1890/4885SMN1; SMN2 1212/4885
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS MAPT 467/4885KDM4E 3740/4885SMN1; SMN2 716/4885
US-11691957-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CCNT1, CCNA1 MAPT 1322/4885KDM4E 4156/4885SMN1; SMN2 2274/4885
US-20240067664-A1 Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device CCND1, CCND2, DRD1 MAPT 3321/4885KDM4E 2966/4885SMN1; SMN2 3283/4885
US-11063228-B2 Metal-assisted delayed fluorescent emitters employing benzo-imidazo-phenanthridine and analogues IK, HELZ, SUN2 MAPT 2476/4885KDM4E 3015/4885SMN1; SMN2 2578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.