SCHEMBL23597018 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	FFAR1	O14842	1/20	0.44

▸	DGAT1	O75907	1/20	0.37

▸	LPL	P06858	9/20	0.37

▸	LIPG	Q9Y5X9	9/20	0.37

▸	HIF1A	Q16665	2/20	0.35

▸	F11	P03951	2/20	0.34

▸	PRMT5	O14744	1/20	0.33

▸	WDR77	Q9BQA1	1/20	0.33

▸	AAK1	Q2M2I8	1/20	0.33

▸	F2	P00734	1/20	0.33

▸	PRSS1	P07477	1/20	0.33

▸	PRSS2	P07478	1/20	0.33

▸	PRSS3	P35030	1/20	0.33

▸	EGFR	P00533	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16008825	0.87	FFAR1 (0.40)	FFAR1DGAT1LPLLIPGHIF1A
SCHEMBL30523101	0.87	FFAR1 (0.40)	FFAR1DGAT1LPLLIPGHIF1A
SCHEMBL22185786	0.86	LPL (0.40)	FFAR1DGAT1LPLLIPGHIF1A
SCHEMBL22289520	0.84	FFAR1 (0.42)	FFAR1DGAT1LPLLIPGHIF1A
SCHEMBL406138	0.83	AR (0.40)	FFAR1LPLLIPGF11F2
SCHEMBL29506948	0.83	AR (0.40)	FFAR1LPLLIPGF11F2
SCHEMBL22977685	0.82	DGAT1 (0.38)	FFAR1DGAT1LPLLIPGHIF1A
SCHEMBL24023348	0.82	LPL (0.37)	FFAR1DGAT1LPLLIPGHIF1A
SCHEMBL12989288	0.81	FFAR1 (0.36)	FFAR1DGAT1LPLLIPGHIF1A
SCHEMBL13195651	0.80	CA1 (0.38)	FFAR1DGAT1LPLLIPGHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021129621-A1	PYRAZOLE COMPOUNDS	江苏先声药业有限公司	2021-07-01	—	—	WO	disclosed