⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766022 | 1.00 | — | — | |
| SCHEMBL134483 | 1.00 | — | — | |
| SCHEMBL15283585 | 0.98 | GPR84 (0.45) | — | |
| SCHEMBL9793919 | 0.98 | GPR84 (0.45) | — | |
| SCHEMBL5705200 | 0.98 | GPR84 (0.45) | — | |
| SCHEMBL15283559 | 0.98 | GPR84 (0.45) | — | |
| SCHEMBL6285996 | 0.98 | GPR84 (0.45) | — | |
| SCHEMBL996234 | 0.98 | GPR84 (0.45) | — | |
| SCHEMBL12994143 | 0.98 | GPR84 (0.45) | — | |
| SCHEMBL1293252 | 0.98 | GPR84 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021552-A1 | SYNTHESIS OF PRO-RESOLVING ANALOGS AND COMPOSITIONS THEREFOR | NOCENDRA INC. (US) | 2021-02-04 | — | — | WO | disclosed |
| US-9783512-B2 | Bicyclic methylene aziridines and reactions thereof | WISCONSIN ALUMI RESEARCH FOUNDATION (US) | 2017-10-10 | — | — | US | disclosed |
| US-9783512-B2 | Bicyclic methylene aziridines and reactions thereof | WISCONSIN ALUMI RESEARCH FOUNDATION (US) | 2017-10-10 | — | — | US | disclosed |
| US-9533049-B2 | Method for preparing nanoparticles based on functional amphiphilic molecules or macromolecules, and the use thereof | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-01-03 | — | — | US | disclosed |
| US-9464033-B2 | Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC. (US) | 2016-10-11 | — | — | US | disclosed |
| US-20160075668-A1 | BICYCLIC METHYLENE AZIRIDINES AND REACTIONS THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2016-03-17 | — | — | US | disclosed |
| US-9221842-B2 | Bicyclic methylene aziridines and reactions thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-12-29 | — | — | US | disclosed |
| US-9221842-B2 | Bicyclic methylene aziridines and reactions thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150329473-A1 | ALKYNYL PHENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA INC. | 2015-11-19 | — | — | US | disclosed |
| EP-2435031-B1 | Functional amphiphilic molecule or macromolecule formulations with multiple compartments | UNIV BORDEAUX (FR) | 2015-09-16 | — | — | EP | disclosed |
| US-4066692-A | 11,12-SECOPROSTAGLANDINS | MERCK & CO., INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-4066675-A | PSORIASIS, THROMBOSIS | MERCK & CO., INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-4059587-A | 8-AZA-9-OXO-11-THIA-PROSTANOIC ACID DERIVATIVES; VASODILATORS, ANTICLOTTING, REGULATORS OF IMMUNE RESPONSE | MERCK & CO., INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-4055597-A | RENAL VASODILATORS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-4046801-A | 13-Cis prostaglandin derivatives | SYNTEX (U.S.A.) INC. (US) | 1977-09-06 | — | — | US | disclosed |
| US-4033996-A | RENAL VASODILATORS, ANTITHROMBOSIS, GROWTH HORMONE RELEASING | MERCK & CO., INC. (US) | 1977-07-05 | — | — | US | disclosed |
| US-4022794-A | VASODILATION | MERCK & CO., INC. (US) | 1977-05-10 | — | — | US | disclosed |
| US-4018802-A | SKIN DISEASES, GROWTH HORMONE STIMULANTS, THROMBUS PREVENTION, IMMUNOLOGY | MERCK & CO., INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-3989749-A | RENAL VASODILATORS, ANTITHROMBUS | MERCK & CO., INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3987091-A | RENAL VASODILATORS | MERCK & CO., INC. (US) | 1976-10-19 | — | — | US | disclosed |